Norcantharidin Enhances High Concentrations of Fetal Bovine Serum-Induced Apoptosis in Human Mesangial Cells by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway

Norcantharidin Enhances High Concentrations of Fetal Bovine Serum-Induced Apoptosis in Human Mesangial Cells by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway

Aim: This study aimed to investigate the effect of norcantharidin (NCTD) on human mesangial cells (HMCs) apoptosis in vitro and further examine its molecular mechanism. Methods: HMCs were divided into 5 groups: control group, 25% fetal bovine serum (FBS)-treated group, and NCTD groups (NCTD [2.5, 5...

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Main Authors: Kun Ye, Qiao-Yu Wei, Teng-Xiang Long, Hong-Guang He, Yun-Feng Huang, Li-Jia Xiong, Jiao Lan, Yi-Yun Huang, Zhi-Feng Gong, Xiao-Mei Peng, Qiu-Xia Wu
Format: Article
Language:English
Published: Karger Publishers 2019-10-01
Series:Kidney & Blood Pressure Research
Subjects:
norcantharidin
human mesangial cells
apoptosis
mitogen-activated protein kinase pathway
Online Access:https://www.karger.com/Article/FullText/502524

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