Messenger RNA Based Vaccines and Their immunological effect on diseases
Because of its capabilities for fast development, potency, secure delivery, and promise for cost effective manufacture, mRNA vaccines are a promising vaccination technique. Many recent research has suggested that mRNA vaccines could be effective intreating a wide range of tumor and viral disorder...
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| Format: | Article |
| Language: | English |
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College of Pharmacy / Mustansiriyah University
2022-07-01
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| Series: | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
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| Online Access: | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/836 |
| _version_ | 1797223943056130048 |
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| author | Osama Mohammed Hasan |
| author_facet | Osama Mohammed Hasan |
| author_sort | Osama Mohammed Hasan |
| collection | DOAJ |
| description |
Because of its capabilities for fast development, potency, secure delivery, and promise for cost effective manufacture, mRNA vaccines are a promising vaccination technique. Many recent research has suggested that mRNA vaccines could be effective intreating a wide range of tumor and viral disorders where standard vaccine techniques have failed to stimulate protective immune responses. The inefficient and unstable in vivo distribution of mRNA has limited their application. Direct electroporation of mRNA vaccines into dendritic cells induced the generation of protective antibodies capable of destroying infected or transformed cells and inducing polyclonal CD8+ and CD4+ that mediated Ag specific T cell responses. in this review mRNA vaccines in detail were examined, as well as future objectives and challenges in the prevention of infectious diseases
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| first_indexed | 2024-04-24T13:45:15Z |
| format | Article |
| id | doaj.art-a708bb800b38495eb25d2dbd0ef82f4a |
| institution | Directory Open Access Journal |
| issn | 1815-0993 2959-183X |
| language | English |
| last_indexed | 2024-04-24T13:45:15Z |
| publishDate | 2022-07-01 |
| publisher | College of Pharmacy / Mustansiriyah University |
| record_format | Article |
| series | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| spelling | doaj.art-a708bb800b38495eb25d2dbd0ef82f4a2024-04-04T06:56:24ZengCollege of Pharmacy / Mustansiriyah UniversityAl-Mustansiriyah Journal of Pharmaceutical Sciences1815-09932959-183X2022-07-0122210.32947/ajps.v22i2.836Messenger RNA Based Vaccines and Their immunological effect on diseases Osama Mohammed Hasan 0Dentistry College / Mustansiriyah University Because of its capabilities for fast development, potency, secure delivery, and promise for cost effective manufacture, mRNA vaccines are a promising vaccination technique. Many recent research has suggested that mRNA vaccines could be effective intreating a wide range of tumor and viral disorders where standard vaccine techniques have failed to stimulate protective immune responses. The inefficient and unstable in vivo distribution of mRNA has limited their application. Direct electroporation of mRNA vaccines into dendritic cells induced the generation of protective antibodies capable of destroying infected or transformed cells and inducing polyclonal CD8+ and CD4+ that mediated Ag specific T cell responses. in this review mRNA vaccines in detail were examined, as well as future objectives and challenges in the prevention of infectious diseases https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/836Mrna, transform cell, immunity, vaccine |
| spellingShingle | Osama Mohammed Hasan Messenger RNA Based Vaccines and Their immunological effect on diseases Al-Mustansiriyah Journal of Pharmaceutical Sciences Mrna, transform cell, immunity, vaccine |
| title | Messenger RNA Based Vaccines and Their immunological effect on diseases |
| title_full | Messenger RNA Based Vaccines and Their immunological effect on diseases |
| title_fullStr | Messenger RNA Based Vaccines and Their immunological effect on diseases |
| title_full_unstemmed | Messenger RNA Based Vaccines and Their immunological effect on diseases |
| title_short | Messenger RNA Based Vaccines and Their immunological effect on diseases |
| title_sort | messenger rna based vaccines and their immunological effect on diseases |
| topic | Mrna, transform cell, immunity, vaccine |
| url | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/836 |
| work_keys_str_mv | AT osamamohammedhasan messengerrnabasedvaccinesandtheirimmunologicaleffectondiseases |