Partial nephrectomy for metastatic renal cell carcinoma: Where do we stand?

Nephron-sparing surgery (NSS) for renal cell carcinoma (RCC) offers comparable oncologic results, but a lower risk of chronic kidney disease, when compared with radical nephrectomy. However, there are limited data in the literature examining the safety of NSS in the setting of metastatic RCC. To eva...

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Main Authors: Mohammed Shahait, Deborah Mukherji, Yaser El-Hout
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Indian Journal of Urology
Subjects:
Online Access:http://www.indianjurol.com/article.asp?issn=0970-1591;year=2015;volume=31;issue=2;spage=102;epage=105;aulast=Shahait
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author Mohammed Shahait
Deborah Mukherji
Yaser El-Hout
author_facet Mohammed Shahait
Deborah Mukherji
Yaser El-Hout
author_sort Mohammed Shahait
collection DOAJ
description Nephron-sparing surgery (NSS) for renal cell carcinoma (RCC) offers comparable oncologic results, but a lower risk of chronic kidney disease, when compared with radical nephrectomy. However, there are limited data in the literature examining the safety of NSS in the setting of metastatic RCC. To evaluate the feasibility of NSS and impact on cancer-specific survival (CSS) in patients with metastatic disease, we performed a systematic review of the literature. There is ample evidence that NSS is feasible in metastatic RCC, with comparable results in terms of CSS compared with radical cytoreductive nephrectomy.
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spelling doaj.art-a709cc892f8c4d0290abf4beda4f3a342022-12-21T17:32:30ZengWolters Kluwer Medknow PublicationsIndian Journal of Urology0970-15911998-38242015-01-0131210210510.4103/0970-1591.154300Partial nephrectomy for metastatic renal cell carcinoma: Where do we stand?Mohammed ShahaitDeborah MukherjiYaser El-HoutNephron-sparing surgery (NSS) for renal cell carcinoma (RCC) offers comparable oncologic results, but a lower risk of chronic kidney disease, when compared with radical nephrectomy. However, there are limited data in the literature examining the safety of NSS in the setting of metastatic RCC. To evaluate the feasibility of NSS and impact on cancer-specific survival (CSS) in patients with metastatic disease, we performed a systematic review of the literature. There is ample evidence that NSS is feasible in metastatic RCC, with comparable results in terms of CSS compared with radical cytoreductive nephrectomy.http://www.indianjurol.com/article.asp?issn=0970-1591;year=2015;volume=31;issue=2;spage=102;epage=105;aulast=ShahaitMetastaticpartial nephrectomyrenal cell carcinoma
spellingShingle Mohammed Shahait
Deborah Mukherji
Yaser El-Hout
Partial nephrectomy for metastatic renal cell carcinoma: Where do we stand?
Indian Journal of Urology
Metastatic
partial nephrectomy
renal cell carcinoma
title Partial nephrectomy for metastatic renal cell carcinoma: Where do we stand?
title_full Partial nephrectomy for metastatic renal cell carcinoma: Where do we stand?
title_fullStr Partial nephrectomy for metastatic renal cell carcinoma: Where do we stand?
title_full_unstemmed Partial nephrectomy for metastatic renal cell carcinoma: Where do we stand?
title_short Partial nephrectomy for metastatic renal cell carcinoma: Where do we stand?
title_sort partial nephrectomy for metastatic renal cell carcinoma where do we stand
topic Metastatic
partial nephrectomy
renal cell carcinoma
url http://www.indianjurol.com/article.asp?issn=0970-1591;year=2015;volume=31;issue=2;spage=102;epage=105;aulast=Shahait
work_keys_str_mv AT mohammedshahait partialnephrectomyformetastaticrenalcellcarcinomawheredowestand
AT deborahmukherji partialnephrectomyformetastaticrenalcellcarcinomawheredowestand
AT yaserelhout partialnephrectomyformetastaticrenalcellcarcinomawheredowestand