An Audio-Based Method for Assessing Proper Usage of Dry Powder Inhalers

Critical technique errors are very often performed by patients in the use of Dry Powder Inhalers (DPIs) resulting in a reduction of the clinical efficiency of such medication. Those critical errors include: pure inhalation, non-arming of the device, no exhalation before or after inhalation, and non-...

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Main Authors: Athina-Chara Eleftheriadou, Anastasios Vafeiadis, Antonios Lalas, Konstantinos Votis, Dimitrios Tzovaras
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/10/19/6677
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author Athina-Chara Eleftheriadou
Anastasios Vafeiadis
Antonios Lalas
Konstantinos Votis
Dimitrios Tzovaras
author_facet Athina-Chara Eleftheriadou
Anastasios Vafeiadis
Antonios Lalas
Konstantinos Votis
Dimitrios Tzovaras
author_sort Athina-Chara Eleftheriadou
collection DOAJ
description Critical technique errors are very often performed by patients in the use of Dry Powder Inhalers (DPIs) resulting in a reduction of the clinical efficiency of such medication. Those critical errors include: pure inhalation, non-arming of the device, no exhalation before or after inhalation, and non-holding of breath for 5–10 s between inhalation and exhalation. In this work, an audio-based classification method that assesses patient DPI user technique is presented by extracting the the non-silent audio segments and categorizing them into respiratory sounds. Twenty healthy and non-healthy volunteers used the same placebo inhaler (Bretaris Genuair Inhaler) in order to evaluate the performance of the algorithm. The audio-based method achieved an F1-score of 89.87% in classifying sound events (<i>Actuation</i>, <i>Inhale</i>, <i>Button Press</i>, and <i>Exhale</i>). The significance of the algorithm lies not just on automatic classification but on a post-processing step of peak detection that resulted in an improvement of 5.58% on the F1-score, reaching 94.85%. This method can provide a clinically accurate assessment of the patient’s inhaler use without the supervision of a doctor.
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spelling doaj.art-a70b3488c9c540289b5f8bf249b5195b2023-11-20T14:56:05ZengMDPI AGApplied Sciences2076-34172020-09-011019667710.3390/app10196677An Audio-Based Method for Assessing Proper Usage of Dry Powder InhalersAthina-Chara Eleftheriadou0Anastasios Vafeiadis1Antonios Lalas2Konstantinos Votis3Dimitrios Tzovaras4Centre for Research and Technology Hellas, Information Technologies Institute, 6th km Charilaou-Thermi, 57001 Thermi, GreeceCentre for Research and Technology Hellas, Information Technologies Institute, 6th km Charilaou-Thermi, 57001 Thermi, GreeceCentre for Research and Technology Hellas, Information Technologies Institute, 6th km Charilaou-Thermi, 57001 Thermi, GreeceCentre for Research and Technology Hellas, Information Technologies Institute, 6th km Charilaou-Thermi, 57001 Thermi, GreeceCentre for Research and Technology Hellas, Information Technologies Institute, 6th km Charilaou-Thermi, 57001 Thermi, GreeceCritical technique errors are very often performed by patients in the use of Dry Powder Inhalers (DPIs) resulting in a reduction of the clinical efficiency of such medication. Those critical errors include: pure inhalation, non-arming of the device, no exhalation before or after inhalation, and non-holding of breath for 5–10 s between inhalation and exhalation. In this work, an audio-based classification method that assesses patient DPI user technique is presented by extracting the the non-silent audio segments and categorizing them into respiratory sounds. Twenty healthy and non-healthy volunteers used the same placebo inhaler (Bretaris Genuair Inhaler) in order to evaluate the performance of the algorithm. The audio-based method achieved an F1-score of 89.87% in classifying sound events (<i>Actuation</i>, <i>Inhale</i>, <i>Button Press</i>, and <i>Exhale</i>). The significance of the algorithm lies not just on automatic classification but on a post-processing step of peak detection that resulted in an improvement of 5.58% on the F1-score, reaching 94.85%. This method can provide a clinically accurate assessment of the patient’s inhaler use without the supervision of a doctor.https://www.mdpi.com/2076-3417/10/19/6677audio classificationmachine learningfeature extractionMFCCsasthmaCOPD
spellingShingle Athina-Chara Eleftheriadou
Anastasios Vafeiadis
Antonios Lalas
Konstantinos Votis
Dimitrios Tzovaras
An Audio-Based Method for Assessing Proper Usage of Dry Powder Inhalers
Applied Sciences
audio classification
machine learning
feature extraction
MFCCs
asthma
COPD
title An Audio-Based Method for Assessing Proper Usage of Dry Powder Inhalers
title_full An Audio-Based Method for Assessing Proper Usage of Dry Powder Inhalers
title_fullStr An Audio-Based Method for Assessing Proper Usage of Dry Powder Inhalers
title_full_unstemmed An Audio-Based Method for Assessing Proper Usage of Dry Powder Inhalers
title_short An Audio-Based Method for Assessing Proper Usage of Dry Powder Inhalers
title_sort audio based method for assessing proper usage of dry powder inhalers
topic audio classification
machine learning
feature extraction
MFCCs
asthma
COPD
url https://www.mdpi.com/2076-3417/10/19/6677
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