IL-22 inhibits bleomycin-induced pulmonary fibrosis in association with inhibition of IL-17A in mice

IL-22 inhibits bleomycin-induced pulmonary fibrosis in association with inhibition of IL-17A in mice

Abstract Background Interstitial lung disease, a common extra-articular complication of connective tissue disease, is characterized by progressive and irreversible pulmonary inflammation and fibrosis, which causes significant mortality. IL-22 shows a potential in regulating chronic inflammation and...

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Bibliographic Details
Main Authors: Ziye Qu, Wencan Dou, Kexin Zhang, Lili Duan, Dongmei Zhou, Songlou Yin
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Arthritis Research & Therapy
Subjects:
IL-22
Bleomycin
Pulmonary fibrosis
IL-17A
Online Access:https://doi.org/10.1186/s13075-022-02977-6

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