GPRC5A Is a Negative Regulator of the Pro-Survival PI3K/Akt Signaling Pathway in Triple-Negative Breast Cancer

GPRC5A Is a Negative Regulator of the Pro-Survival PI3K/Akt Signaling Pathway in Triple-Negative Breast Cancer

Breast cancer is one of the most common types of malignancy worldwide; however, its underlying mechanisms remain unclear. In the present study, we investigated the roles of G-protein-coupled receptor family C, member 5, group A (GPRC5A) in cell apoptosis in triple-negative breast cancer (TNBC). The...

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Bibliographic Details
Main Authors: Lu Yang, Shaorong Zhao, Tong Zhu, Jin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
G-protein-coupled receptor family C
member 5
group A (Gprc5a)
cell apoptosis
PI3K/Akt
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.624493/full

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