Targeting BCR-ABL1-positive leukaemias: a review article

Targeting BCR-ABL1-positive leukaemias: a review article

Treatment and understanding of BCR::ABL1-positive leukaemias is a precision medicine success story. Our appreciation of the BCR::ABL1 gene and resulting BCR::ABL1 oncoprotein in chronic myeloid leukaemia (CML) and Philadelphia chromosome-positive (Ph+) acute leukaemias, has led to treatment advances...

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Bibliographic Details
Main Authors: Steven Leak, Gillian A. Horne, Mhairi Copland
Format: Article
Language:English
Published: Cambridge University Press 2023-01-01
Series:Cambridge Prisms: Precision Medicine
Subjects:
Chronic myeloid leukaemia
tyrosine kinase inhibitor
leukaemia stem cell
BCR::ABL1
Online Access:https://www.cambridge.org/core/product/identifier/S2752614323000091/type/journal_article

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