HGF/c-Met related activation of β-catenin in hepatoblastoma

HGF/c-Met related activation of β-catenin in hepatoblastoma

<p>Abstract</p> <p>Background</p> <p>Activation of beta-catenin is a hallmark of hepatoblastoma (HB) and appears to play a crucial role in its pathogenesis. While aberrant accumulation of the beta-catenin is a common event in HB, mutations or deletions in CTNNB1 (beta-c...

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Bibliographic Details
Main Authors: Turner Clinton, Miles Carina, Maibach Rudolf, Childs Margaret, Purcell Rachel, Zimmermann Arthur, Sullivan Michael
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/30/1/96

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