Defective angiogenesis in CXCL12 mutant mice impairs skeletal muscle regeneration
Abstract Background During muscle regeneration, the chemokine CXCL12 (SDF-1) and the synthesis of some specific heparan sulfates (HS) have been shown to be critical. CXCL12 activity has been shown to be heavily influenced by its binding to extracellular glycosaminoglycans (GAG) by modulating its pre...
Main Authors: | David Hardy, Mylène Fefeu, Aurore Besnard, David Briand, Paméla Gasse, Fernando Arenzana-Seisdedos, Pierre Rocheteau, Fabrice Chrétien |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-09-01
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Series: | Skeletal Muscle |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13395-019-0210-5 |
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