Agarose/crystalline nanocellulose (CNC) composites promote bone marrow-derived mast cell integrity, degranulation and receptor expression but inhibit production of de novo synthesized mediators

Agarose/crystalline nanocellulose (CNC) composites promote bone marrow-derived mast cell integrity, degranulation and receptor expression but inhibit production of de novo synthesized mediators

Introduction: Mast cells are highly granulated tissue-resident leukocytes that require a three-dimensional matrix to differentiate and mediate immune responses. However, almost all cultured mast cells rely on two-dimensional suspension or adherent cell culture systems, which do not adequately reflec...

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Bibliographic Details
Main Authors: Marianna Kulka, Ashley Wagner, Jae-Young Cho, Syed Benazir Alam, Joy Ramielle Santos, Juan Jovel, Leshern Karamchand, Marcelo Marcet-Palacios
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mast cell
nanocellulose
cytokines
inflammation
IgE
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1160460/full

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