Subtypes and Mechanistic Advances of Extracorporeal Membrane Oxygenation-Related Acute Brain Injury
Extracorporeal membrane oxygenation (ECMO) is a frequently used mechanical cardiopulmonary support for rescuing critically ill patients for whom conventional medical therapies have failed. However, ECMO is associated with several complications, such as acute kidney injury, hemorrhage, thromboembolis...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/13/8/1165 |
| _version_ | 1797585334566912000 |
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| author | Bixin Deng Junjie Ying Dezhi Mu |
| author_facet | Bixin Deng Junjie Ying Dezhi Mu |
| author_sort | Bixin Deng |
| collection | DOAJ |
| description | Extracorporeal membrane oxygenation (ECMO) is a frequently used mechanical cardiopulmonary support for rescuing critically ill patients for whom conventional medical therapies have failed. However, ECMO is associated with several complications, such as acute kidney injury, hemorrhage, thromboembolism, and acute brain injury (ABI). Among these, ABI, particularly intracranial hemorrhage (ICH) and infarction, is recognized as the primary cause of mortality during ECMO support. Furthermore, survivors often suffer significant long-term morbidities, including neurocognitive impairments, motor disturbances, and behavioral problems. This review provides a comprehensive overview of the different subtypes of ECMO-related ABI and the updated advance mechanisms, which could be helpful for the early diagnosis and potential neuromonitoring of ECMO-related ABI. |
| first_indexed | 2024-03-11T00:05:39Z |
| format | Article |
| id | doaj.art-a7166eddb04040deb9f42d4c2f5b5ce0 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-11T00:05:39Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-a7166eddb04040deb9f42d4c2f5b5ce02023-11-19T00:26:40ZengMDPI AGBrain Sciences2076-34252023-08-01138116510.3390/brainsci13081165Subtypes and Mechanistic Advances of Extracorporeal Membrane Oxygenation-Related Acute Brain InjuryBixin Deng0Junjie Ying1Dezhi Mu2Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, ChinaKey Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu 610041, ChinaDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, ChinaExtracorporeal membrane oxygenation (ECMO) is a frequently used mechanical cardiopulmonary support for rescuing critically ill patients for whom conventional medical therapies have failed. However, ECMO is associated with several complications, such as acute kidney injury, hemorrhage, thromboembolism, and acute brain injury (ABI). Among these, ABI, particularly intracranial hemorrhage (ICH) and infarction, is recognized as the primary cause of mortality during ECMO support. Furthermore, survivors often suffer significant long-term morbidities, including neurocognitive impairments, motor disturbances, and behavioral problems. This review provides a comprehensive overview of the different subtypes of ECMO-related ABI and the updated advance mechanisms, which could be helpful for the early diagnosis and potential neuromonitoring of ECMO-related ABI.https://www.mdpi.com/2076-3425/13/8/1165extracorporeal membrane oxygenationcritical illnessacute brain injurymorbidityhemodynamics |
| spellingShingle | Bixin Deng Junjie Ying Dezhi Mu Subtypes and Mechanistic Advances of Extracorporeal Membrane Oxygenation-Related Acute Brain Injury Brain Sciences extracorporeal membrane oxygenation critical illness acute brain injury morbidity hemodynamics |
| title | Subtypes and Mechanistic Advances of Extracorporeal Membrane Oxygenation-Related Acute Brain Injury |
| title_full | Subtypes and Mechanistic Advances of Extracorporeal Membrane Oxygenation-Related Acute Brain Injury |
| title_fullStr | Subtypes and Mechanistic Advances of Extracorporeal Membrane Oxygenation-Related Acute Brain Injury |
| title_full_unstemmed | Subtypes and Mechanistic Advances of Extracorporeal Membrane Oxygenation-Related Acute Brain Injury |
| title_short | Subtypes and Mechanistic Advances of Extracorporeal Membrane Oxygenation-Related Acute Brain Injury |
| title_sort | subtypes and mechanistic advances of extracorporeal membrane oxygenation related acute brain injury |
| topic | extracorporeal membrane oxygenation critical illness acute brain injury morbidity hemodynamics |
| url | https://www.mdpi.com/2076-3425/13/8/1165 |
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