Yes-associated protein-1 overexpression in ocular surface squamous neoplasia; a potential diagnostic marker and therapeutic target

Yes-associated protein-1 overexpression in ocular surface squamous neoplasia; a potential diagnostic marker and therapeutic target

Yes-associated protein-1 (YAP-1) is a Hippo system transcription factor, which serves as an oncogene in squamous cell carcinoma, and several solid tumors when the Hippo pathway is dysregulated. Yet, the activity of YAP-1 in ocular surface squamous neoplasia (OSSN) has not been determined. Here, we i...

Full description

Bibliographic Details
Main Authors: Peter Julius, Stepfanie N. Siyumbwa, Fred Maate, Phyllis Moonga, Guobin Kang, Trevor Kaile, John T. West, Charles Wood, Peter C. Angeletti
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Oncology
Subjects:
yes-associated protein-1 (YAP-1)
ocular surface squamous neoplasia (OSSN)
preinvasive OSSN
invasive OSSN
Zambia
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1213426/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1213426/full

Similar Items