The Study on Electrochemical Behaviors of the Interactions between Daunorubicin Hydrochloride and BSA
The Electrochemical behaviors of Daunorubicin hydrochloride, and the interactions between Daunorubicin hydrochloride and BSA, were studied in this paper, with Linear sweep voltammetry and Cyclic voltammety methods. The results showed that, there was a reductive peak at E=-0.66V in the Linear sweep v...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Tsinghua University Press
2010-06-01
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| Series: | Nano Biomedicine and Engineering |
| Subjects: | |
| Online Access: | https://www.sciopen.com/article/10.5101/nbe.v2i2.p138-142 |
| _version_ | 1797673532516204544 |
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| author | Jie Liu Bo Zhang |
| author_facet | Jie Liu Bo Zhang |
| author_sort | Jie Liu |
| collection | DOAJ |
| description | The Electrochemical behaviors of Daunorubicin hydrochloride, and the interactions between Daunorubicin hydrochloride and BSA, were studied in this paper, with Linear sweep voltammetry and Cyclic voltammety methods. The results showed that, there was a reductive peak at E=-0.66V in the Linear sweep voltammetry of Daunorubicin hydrochloride, on condition of 0.1 mol·L-1Na2SO4, pH 8.5B-R buffer solution. After BSA was introduced, the system peak current reduced. There was a maximal system peak current Δip″, when the concentration of Daunorubicin hydrochloride was 5.0×10-5 mol·L-1. At the range of 5.0×10-8 mol·L-1-1.0×10-4 mol·L-1 of the concentration of BSA, it existed a good linear relation between the reduced valve of the peak current of Daunorubicin hydrochloride and the concentration of BSA. This method can be used in the detection of the concentration of BSA. |
| first_indexed | 2024-03-11T21:45:48Z |
| format | Article |
| id | doaj.art-a7187e8f393b4a2eb319672f28a6f03a |
| institution | Directory Open Access Journal |
| issn | 2150-5578 |
| language | English |
| last_indexed | 2024-03-11T21:45:48Z |
| publishDate | 2010-06-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Nano Biomedicine and Engineering |
| spelling | doaj.art-a7187e8f393b4a2eb319672f28a6f03a2023-09-26T10:12:26ZengTsinghua University PressNano Biomedicine and Engineering2150-55782010-06-012213814210.5101/nbe.v2i2.p138-142The Study on Electrochemical Behaviors of the Interactions between Daunorubicin Hydrochloride and BSAJie Liu0Bo Zhang1Taiyuan City Centre Hospital, Taiyuan, 030009Taiyuan City Centre Hospital, Taiyuan, 030009The Electrochemical behaviors of Daunorubicin hydrochloride, and the interactions between Daunorubicin hydrochloride and BSA, were studied in this paper, with Linear sweep voltammetry and Cyclic voltammety methods. The results showed that, there was a reductive peak at E=-0.66V in the Linear sweep voltammetry of Daunorubicin hydrochloride, on condition of 0.1 mol·L-1Na2SO4, pH 8.5B-R buffer solution. After BSA was introduced, the system peak current reduced. There was a maximal system peak current Δip″, when the concentration of Daunorubicin hydrochloride was 5.0×10-5 mol·L-1. At the range of 5.0×10-8 mol·L-1-1.0×10-4 mol·L-1 of the concentration of BSA, it existed a good linear relation between the reduced valve of the peak current of Daunorubicin hydrochloride and the concentration of BSA. This method can be used in the detection of the concentration of BSA.https://www.sciopen.com/article/10.5101/nbe.v2i2.p138-142daunorubicin hydrochloridebovine serum albuminelectrochemical behaviorslinear sweep voltammetrycyclic voltammety |
| spellingShingle | Jie Liu Bo Zhang The Study on Electrochemical Behaviors of the Interactions between Daunorubicin Hydrochloride and BSA Nano Biomedicine and Engineering daunorubicin hydrochloride bovine serum albumin electrochemical behaviors linear sweep voltammetry cyclic voltammety |
| title | The Study on Electrochemical Behaviors of the Interactions between Daunorubicin Hydrochloride and BSA |
| title_full | The Study on Electrochemical Behaviors of the Interactions between Daunorubicin Hydrochloride and BSA |
| title_fullStr | The Study on Electrochemical Behaviors of the Interactions between Daunorubicin Hydrochloride and BSA |
| title_full_unstemmed | The Study on Electrochemical Behaviors of the Interactions between Daunorubicin Hydrochloride and BSA |
| title_short | The Study on Electrochemical Behaviors of the Interactions between Daunorubicin Hydrochloride and BSA |
| title_sort | study on electrochemical behaviors of the interactions between daunorubicin hydrochloride and bsa |
| topic | daunorubicin hydrochloride bovine serum albumin electrochemical behaviors linear sweep voltammetry cyclic voltammety |
| url | https://www.sciopen.com/article/10.5101/nbe.v2i2.p138-142 |
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