Identification and functional analysis of SOX10 phosphorylation sites in melanoma.
The transcription factor SOX10 plays an important role in vertebrate neural crest development, including the establishment and maintenance of the melanocyte lineage. SOX10 is also highly expressed in melanoma tumors, and SOX10 expression increases with tumor progression. The suppression of SOX10 in...
Main Authors: | Julia C Cronin, Stacie K Loftus, Laura L Baxter, Steve Swatkoski, Marjan Gucek, William J Pavan |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5760019?pdf=render |
Similar Items
-
MEK inhibition remodels the active chromatin landscape and induces SOX10 genomic recruitment in BRAF(V600E) mutant melanoma cells
by: Temesgen D. Fufa, et al.
Published: (2019-08-01) -
ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma
by: Shujun Han, et al.
Published: (2018-01-01) -
Identification of neural crest and glial enhancers at the mouse Sox10 locus through transgenesis in zebrafish.
by: Anthony Antonellis, et al.
Published: (2008-09-01) -
A Sox10 expression screen identifies an amino acid essential for Erbb3 function.
by: Kristina Buac, et al.
Published: (2008-09-01) -
Publisher Correction: ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma
by: Shujun Han, et al.
Published: (2018-04-01)