Identification and functional analysis of SOX10 phosphorylation sites in melanoma.

The transcription factor SOX10 plays an important role in vertebrate neural crest development, including the establishment and maintenance of the melanocyte lineage. SOX10 is also highly expressed in melanoma tumors, and SOX10 expression increases with tumor progression. The suppression of SOX10 in...

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Bibliographic Details
Main Authors: Julia C Cronin, Stacie K Loftus, Laura L Baxter, Steve Swatkoski, Marjan Gucek, William J Pavan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5760019?pdf=render

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