Mizoribine provides effective treatment of sequential histological change of arteritis and reduction of inflammatory cytokines and chemokines in an animal model of Kawasaki disease

Mizoribine provides effective treatment of sequential histological change of arteritis and reduction of inflammatory cytokines and chemokines in an animal model of Kawasaki disease

<p>Abstract</p> <p>Background</p> <p>Intravenous immunoglobulin (IVIg) treatment results in an effective response from patients with acute-phase Kawasaki disease (KD), but 16.5% of them remain nonresponsive to IVIg. To address this therapeutic challenge, we tried a new...

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Bibliographic Details
Main Authors: Ohno Naohito, Nagi-Miura Noriko, Yamada Hitomi, Yokouchi Yuki, Nagao Tomokazu, Oharaseki Toshiaki, Takahashi Kei, Saji Tsutomu, Okazaki Tomio, Suzuki Kazuo
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Pediatric Rheumatology Online Journal
Subjects:
Kawasaki disease
an animal model
IVIg
coronary arteritis
inflammatory cytokines and chemokines
mizoribine
Online Access:http://www.ped-rheum.com/content/9/1/30

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