PATHWAYS OF RECOGNITION OF FOREIGN ANTIGENS IN THE ADAPTIVE IMMUNE RESPONSE TO ALLOGENEIC ORGAN TRANSPLANTATION

PATHWAYS OF RECOGNITION OF FOREIGN ANTIGENS IN THE ADAPTIVE IMMUNE RESPONSE TO ALLOGENEIC ORGAN TRANSPLANTATION

Immunological allograft rejection is based on the process of recognition of donor antigens by T-cell receptors. Antigens are generally represented by molecules of major hystocompatibility complex (MHC), expressed by the donor organ tissue cells. Immune response to allogeneic transplant in its activi...

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Bibliographic Details
Main Authors: A. S. Berkos, G. V. Nikolaev
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2016-01-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
allograft
allorecognition
major histocompatibility complex
antigen presenting cells
t-cell receptor
Online Access:https://journal.transpl.ru/vtio/article/view/597

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