A Case-Control Study of Paracoccidioidomycosis in Women: The Hormonal Protection Revisited

A Case-Control Study of Paracoccidioidomycosis in Women: The Hormonal Protection Revisited

Clinical observations have long suggested that women are protected against paracoccidioidomycosis. 17β-estradiol, the main female estrogen, inhibits conidia-to-yeast transformation (C-to-Y), which is required for the infection establishment. However, experiments in murine models have yielded conflic...

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Bibliographic Details
Main Authors: Tereza Graciano Nascimento de Brito, Mariane Taborda, Bruna Provenci, André Nathan Costa, Gil Benard
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Fungi
Subjects:
paracoccidioidomycosis
estrogens
female
susceptibility
skin test
Online Access:https://www.mdpi.com/2309-608X/7/8/655

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