Hydrolysable chestnut tannins for reduction of postweaning diarrhea: Efficacy on an experimental ETEC F4 model.
An experimental model for postweaning diarrhea with enterotoxigenic Escherichia coli F4 (ETEC F4) was set up in piglets, and the efficacy of 1% chestnut-tannin extract in preventing diarrhea was subsequently assessed. In a first trial (infection model), 32 Swiss Large White piglets (age: 24 days; av...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2018-01-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5969761?pdf=render |
| _version_ | 1818922949815566336 |
|---|---|
| author | Marion Girard Sophie Thanner Nicolas Pradervand Dou Hu Catherine Ollagnier Giuseppe Bee |
| author_facet | Marion Girard Sophie Thanner Nicolas Pradervand Dou Hu Catherine Ollagnier Giuseppe Bee |
| author_sort | Marion Girard |
| collection | DOAJ |
| description | An experimental model for postweaning diarrhea with enterotoxigenic Escherichia coli F4 (ETEC F4) was set up in piglets, and the efficacy of 1% chestnut-tannin extract in preventing diarrhea was subsequently assessed. In a first trial (infection model), 32 Swiss Large White piglets (age: 24 days; average BW: 7.8 ± 0.8 kg) were randomly assigned to two experimental groups (infected [INF], noninfected [NINF]). In a subsequent trial, 72 Swiss Large White piglets (age: 26 days; average BW: 7.4 ± 1.5 kg) were blocked by BW and assigned within block to four experimental groups: NINF-CO: not infected and fed a standard control starter diet (CO); INF-CO: infected and fed the CO diet; NINF-TA: not infected and fed the CO diet supplemented with 1% chestnut extract containing 54% of hydrolysable tannins (TA); and INF-TA: infected and fed the TA diet. Both diets (TA and CO) were formulated to be isocaloric and isoproteic and to meet or surpass the nutritional requirements. In both trials, four days after weaning, piglets assigned to the INF group received an oral suspension of ETEC F4. Fecal score, ETEC shedding in feces (only in trial 2), and growth performance traits were measured for the following 14 days post infection. In both trials, more than 50% of the INF piglets developed diarrhea within six days post infection. Tannins reduced (P < 0.05) the average fecal score, the percentage of piglets in diarrhea, and the duration of diarrhea, whereas feed intake and the average daily gain were unaffected. |
| first_indexed | 2024-12-20T02:01:40Z |
| format | Article |
| id | doaj.art-a7214aa69567440f801c0d42e2405034 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T02:01:40Z |
| publishDate | 2018-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-a7214aa69567440f801c0d42e24050342022-12-21T19:57:19ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01135e019787810.1371/journal.pone.0197878Hydrolysable chestnut tannins for reduction of postweaning diarrhea: Efficacy on an experimental ETEC F4 model.Marion GirardSophie ThannerNicolas PradervandDou HuCatherine OllagnierGiuseppe BeeAn experimental model for postweaning diarrhea with enterotoxigenic Escherichia coli F4 (ETEC F4) was set up in piglets, and the efficacy of 1% chestnut-tannin extract in preventing diarrhea was subsequently assessed. In a first trial (infection model), 32 Swiss Large White piglets (age: 24 days; average BW: 7.8 ± 0.8 kg) were randomly assigned to two experimental groups (infected [INF], noninfected [NINF]). In a subsequent trial, 72 Swiss Large White piglets (age: 26 days; average BW: 7.4 ± 1.5 kg) were blocked by BW and assigned within block to four experimental groups: NINF-CO: not infected and fed a standard control starter diet (CO); INF-CO: infected and fed the CO diet; NINF-TA: not infected and fed the CO diet supplemented with 1% chestnut extract containing 54% of hydrolysable tannins (TA); and INF-TA: infected and fed the TA diet. Both diets (TA and CO) were formulated to be isocaloric and isoproteic and to meet or surpass the nutritional requirements. In both trials, four days after weaning, piglets assigned to the INF group received an oral suspension of ETEC F4. Fecal score, ETEC shedding in feces (only in trial 2), and growth performance traits were measured for the following 14 days post infection. In both trials, more than 50% of the INF piglets developed diarrhea within six days post infection. Tannins reduced (P < 0.05) the average fecal score, the percentage of piglets in diarrhea, and the duration of diarrhea, whereas feed intake and the average daily gain were unaffected.http://europepmc.org/articles/PMC5969761?pdf=render |
| spellingShingle | Marion Girard Sophie Thanner Nicolas Pradervand Dou Hu Catherine Ollagnier Giuseppe Bee Hydrolysable chestnut tannins for reduction of postweaning diarrhea: Efficacy on an experimental ETEC F4 model. PLoS ONE |
| title | Hydrolysable chestnut tannins for reduction of postweaning diarrhea: Efficacy on an experimental ETEC F4 model. |
| title_full | Hydrolysable chestnut tannins for reduction of postweaning diarrhea: Efficacy on an experimental ETEC F4 model. |
| title_fullStr | Hydrolysable chestnut tannins for reduction of postweaning diarrhea: Efficacy on an experimental ETEC F4 model. |
| title_full_unstemmed | Hydrolysable chestnut tannins for reduction of postweaning diarrhea: Efficacy on an experimental ETEC F4 model. |
| title_short | Hydrolysable chestnut tannins for reduction of postweaning diarrhea: Efficacy on an experimental ETEC F4 model. |
| title_sort | hydrolysable chestnut tannins for reduction of postweaning diarrhea efficacy on an experimental etec f4 model |
| url | http://europepmc.org/articles/PMC5969761?pdf=render |
| work_keys_str_mv | AT mariongirard hydrolysablechestnuttanninsforreductionofpostweaningdiarrheaefficacyonanexperimentaletecf4model AT sophiethanner hydrolysablechestnuttanninsforreductionofpostweaningdiarrheaefficacyonanexperimentaletecf4model AT nicolaspradervand hydrolysablechestnuttanninsforreductionofpostweaningdiarrheaefficacyonanexperimentaletecf4model AT douhu hydrolysablechestnuttanninsforreductionofpostweaningdiarrheaefficacyonanexperimentaletecf4model AT catherineollagnier hydrolysablechestnuttanninsforreductionofpostweaningdiarrheaefficacyonanexperimentaletecf4model AT giuseppebee hydrolysablechestnuttanninsforreductionofpostweaningdiarrheaefficacyonanexperimentaletecf4model |