Serotonin-evoked cytosolic Ca2+ release and opioid receptor expression are upregulated in articular cartilage chondrocytes from osteoarthritic joints in horses
Osteoarthritis is a pain-associated progressive disease and pain mediators, such as opioid receptors, expressed in articular cartilage could represent novel therapeutic targets. Acute and chronic stages of OA indicate different metabolic abilities of the chondrocytes depending on inflammatory state....
Main Authors: | Eva Skiöldebrand, Cecilia Ley, Ulrika Björklund, Anders Lindahl, Elisabeth Hansson |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2019-12-01
|
Series: | Veterinary and Animal Science |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2451943X19301292 |
Similar Items
-
Alloreactivity and Immunosuppressive Properties of Articular Chondrocytes from Osteoarthritic Cartilage
by: Satomi Abe, et al.
Published: (2016-08-01) -
Bupivacaine in combination with sildenafil (Viagra) and vitamin D3 have anti-inflammatory effects in osteoarthritic chondrocytes
by: Elisabeth Hansson, et al.
Published: (2021-01-01) -
Biochemical alterations in inflammatory reactive chondrocytes: evidence for intercellular network communication
by: Eva Skiöldebrand, et al.
Published: (2018-01-01) -
In vitro evaluation of chondrocytes isolated from osteoarthritic articular cartilage supplemented with edible bird's nest extract /
by: Kamini Nagandran, 1980-, et al.
Published: (2011) -
Comparison of immunogenic markers of human chondrocytes and chondroprogenitors derived from non-diseased and osteoarthritic articular cartilage
by: Elizabeth Vinod, et al.
Published: (2020-06-01)