Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway

Aspirin has a better effect on PIK3CA mutant colorectal cancer cells by PI3K/Akt/Raptor pathway

Abstract Background Aspirin, as a non-steroidal anti-inflammatory drug, can improve the survival rate of patients with colorectal cancer, while aspirin is effective in patients with PIK3CA mutant colorectal cancer (CRC). However, the mechanism of aspirin in the treatment of PIK3CA mutated CRC patien...

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Bibliographic Details
Main Authors: Zhihang Chen, Chun Wang, Hao Dong, Xing Wang, Feng Gao, Sen Zhang, Xiaolong Zhang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Molecular Medicine
Subjects:
Colorectal cancer
Aspirin
PI3K/Akt/raptor pathway
PIK3CA mutated
Online Access:https://doi.org/10.1186/s10020-020-0139-5

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