Solvent effects on the crystallization and structure of ternary copper(ii) coordination compounds with l-threonine and 1,10-phenanthroline
Solution-based and solid-state reactions of copper(ii) compounds, 1,10-phenanthroline and l-threonine were investigated. Eight new ternary coordination compounds were obtained:[Cu(l-Thr)(H2O)(phen)]2SO4∙10H2O (1a∙10H2O), [Cu(l-Thr)(H2O) (phen)]2SO4∙4.3H2O (1a∙4.3H2O), {[Cu(μ-l-Thr)(phen)]2SO4∙3.5H2O...
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| Language: | English |
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Elsevier
2022-06-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844022008441 |
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| author | Darko Vušak Katarina Ležaić Jurica Jurec Dijana Žilić Biserka Prugovečki |
| author_facet | Darko Vušak Katarina Ležaić Jurica Jurec Dijana Žilić Biserka Prugovečki |
| author_sort | Darko Vušak |
| collection | DOAJ |
| description | Solution-based and solid-state reactions of copper(ii) compounds, 1,10-phenanthroline and l-threonine were investigated. Eight new ternary coordination compounds were obtained:[Cu(l-Thr)(H2O)(phen)]2SO4∙10H2O (1a∙10H2O), [Cu(l-Thr)(H2O) (phen)]2SO4∙4.3H2O (1a∙4.3H2O), {[Cu(μ-l-Thr)(phen)]2SO4∙3.5H2O}n (1b∙3.5H2O), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)]SO4∙2H2O∙CH3OH (1c∙2H2O∙CH3OH), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)]SO4∙4H2O (1c∙4H2O), [Cu(l-Thr)(CH3OH)(phen)]2SO4∙H2O (1d∙H2O), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)][Cu(SO4)(l-Thr)(phen)]HSO4∙H2O∙3CH3OH (1e·H2O·3CH3OH), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(phen)(py)]SO4 (1f) (phen = 1,10-phenanthroline, l-Thr = l-threoninate, py = pyridine). X-ray crystal structure analysis of the prepared ternary coordination compounds revealed extensive hydrogen bonding and π-interactions that link complex species, anions and solvent molecules into 3D architectures. The water/methanol solvent molecules are found in pockets and/or channels in seven solvates. ESR spectra of different types of compounds were also investigated. In all measured compounds the unpaired electron of the copper(II) ion is located in the dx2-y2 orbital which is in agreement with elongated square-pyramidal geometry. Compound 1a∙10H2O showed substantial cytotoxic activity toward human hepatocellular carcinoma (HepG2) and acute monocytic leukaemia (THP-1) cell lines. |
| first_indexed | 2024-04-12T12:56:16Z |
| format | Article |
| id | doaj.art-a72474663a6648839b39b11cce767eb0 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-12T12:56:16Z |
| publishDate | 2022-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-a72474663a6648839b39b11cce767eb02022-12-22T03:32:20ZengElsevierHeliyon2405-84402022-06-0186e09556Solvent effects on the crystallization and structure of ternary copper(ii) coordination compounds with l-threonine and 1,10-phenanthrolineDarko Vušak0Katarina Ležaić1Jurica Jurec2Dijana Žilić3Biserka Prugovečki4Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, HR-10000, Zagreb, CroatiaDepartment of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, HR-10000, Zagreb, CroatiaLaboratory for Magnetic Resonances, Division of Physical Chemistry, Ruđer Bošković Institute, Bijenička 54, HR-10000 Zagreb, CroatiaLaboratory for Magnetic Resonances, Division of Physical Chemistry, Ruđer Bošković Institute, Bijenička 54, HR-10000 Zagreb, CroatiaDepartment of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, HR-10000, Zagreb, Croatia; Corresponding author.Solution-based and solid-state reactions of copper(ii) compounds, 1,10-phenanthroline and l-threonine were investigated. Eight new ternary coordination compounds were obtained:[Cu(l-Thr)(H2O)(phen)]2SO4∙10H2O (1a∙10H2O), [Cu(l-Thr)(H2O) (phen)]2SO4∙4.3H2O (1a∙4.3H2O), {[Cu(μ-l-Thr)(phen)]2SO4∙3.5H2O}n (1b∙3.5H2O), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)]SO4∙2H2O∙CH3OH (1c∙2H2O∙CH3OH), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)]SO4∙4H2O (1c∙4H2O), [Cu(l-Thr)(CH3OH)(phen)]2SO4∙H2O (1d∙H2O), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(CH3OH)(phen)][Cu(SO4)(l-Thr)(phen)]HSO4∙H2O∙3CH3OH (1e·H2O·3CH3OH), [Cu(l-Thr)(H2O)(phen)][Cu(l-Thr)(phen)(py)]SO4 (1f) (phen = 1,10-phenanthroline, l-Thr = l-threoninate, py = pyridine). X-ray crystal structure analysis of the prepared ternary coordination compounds revealed extensive hydrogen bonding and π-interactions that link complex species, anions and solvent molecules into 3D architectures. The water/methanol solvent molecules are found in pockets and/or channels in seven solvates. ESR spectra of different types of compounds were also investigated. In all measured compounds the unpaired electron of the copper(II) ion is located in the dx2-y2 orbital which is in agreement with elongated square-pyramidal geometry. Compound 1a∙10H2O showed substantial cytotoxic activity toward human hepatocellular carcinoma (HepG2) and acute monocytic leukaemia (THP-1) cell lines.http://www.sciencedirect.com/science/article/pii/S2405844022008441Ternary coordination compoundsSolvatomorphsCrystal structuresESR spectraSolution-based synthesisMechanochemical synthesis |
| spellingShingle | Darko Vušak Katarina Ležaić Jurica Jurec Dijana Žilić Biserka Prugovečki Solvent effects on the crystallization and structure of ternary copper(ii) coordination compounds with l-threonine and 1,10-phenanthroline Heliyon Ternary coordination compounds Solvatomorphs Crystal structures ESR spectra Solution-based synthesis Mechanochemical synthesis |
| title | Solvent effects on the crystallization and structure of ternary copper(ii) coordination compounds with l-threonine and 1,10-phenanthroline |
| title_full | Solvent effects on the crystallization and structure of ternary copper(ii) coordination compounds with l-threonine and 1,10-phenanthroline |
| title_fullStr | Solvent effects on the crystallization and structure of ternary copper(ii) coordination compounds with l-threonine and 1,10-phenanthroline |
| title_full_unstemmed | Solvent effects on the crystallization and structure of ternary copper(ii) coordination compounds with l-threonine and 1,10-phenanthroline |
| title_short | Solvent effects on the crystallization and structure of ternary copper(ii) coordination compounds with l-threonine and 1,10-phenanthroline |
| title_sort | solvent effects on the crystallization and structure of ternary copper ii coordination compounds with l threonine and 1 10 phenanthroline |
| topic | Ternary coordination compounds Solvatomorphs Crystal structures ESR spectra Solution-based synthesis Mechanochemical synthesis |
| url | http://www.sciencedirect.com/science/article/pii/S2405844022008441 |
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