Helicobacter pylori infection in a multi-ethnic population in east coast of Borneo, Malaysia: The effects of ethnicity
Objective: To determine the prevalence of Helicobacter (H.) pylori infection among the population of east coast of Borneo and explore the relationship between demographic factors, ethnicity and risk of H. pylori infection. Methods: This cross-sectional study enrolled 211 patients who underwent elect...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | One Health Bulletin |
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| Online Access: | http://www.johb.info/article.asp?issn=2773-0344;year=2022;volume=2;issue=1;spage=4;epage=4;aulast=Lee |
| _version_ | 1797322308254171136 |
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| author | Ooi-Cheng Lee Chung-Ket Lai |
| author_facet | Ooi-Cheng Lee Chung-Ket Lai |
| author_sort | Ooi-Cheng Lee |
| collection | DOAJ |
| description | Objective: To determine the prevalence of Helicobacter (H.) pylori infection among the population of east coast of Borneo and explore the relationship between demographic factors, ethnicity and risk of H. pylori infection.
Methods: This cross-sectional study enrolled 211 patients who underwent elective oesophagogastroduodenoscopy in 2017. Demographic data, endoscopic indications as well as the results of the mucosal biopsy were obtained and analysed from the endoscopy unit registry.
Results: A total of 211 patients from 14 ethnic groups were enrolled in the study, most of were Chinese (28.4%), followed by Dusun (14.7%) and Songgai (13.7%). Overall, the period prevalence for 2017 was 44.5%. Multivariate logistic regression analysis showed an association between ethnicity and H. pylori. Bajau (adjusted odds ratio=5.612, P=0.005) and Dusun ethnic groups (adjusted odds ratio=7.359, P=0.001) were at a significantly higher risk of H. pylori infection compared to Chinese. However, the regression model only explained 11.6% (Cox & Snell Pseudo R2) of the prevalence of H. pylori infection.
Conclusions: The period prevalence for 2017 was 44.5%, with certain indigenous ethnic groups having a higher risk than others. Clinicians should consider obtaining further history regarding the ethnic’s culture and dietary practice prior to starting H. pylori eradication therapy. |
| first_indexed | 2024-03-08T05:11:24Z |
| format | Article |
| id | doaj.art-a72523e13bd84bb6b866427dd51ad383 |
| institution | Directory Open Access Journal |
| issn | 2773-0344 2773-0352 |
| language | English |
| last_indexed | 2024-03-08T05:11:24Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | One Health Bulletin |
| spelling | doaj.art-a72523e13bd84bb6b866427dd51ad3832024-02-07T09:10:01ZengWolters Kluwer Medknow PublicationsOne Health Bulletin2773-03442773-03522022-01-01214410.4103/2773-0344.345316Helicobacter pylori infection in a multi-ethnic population in east coast of Borneo, Malaysia: The effects of ethnicityOoi-Cheng LeeChung-Ket LaiObjective: To determine the prevalence of Helicobacter (H.) pylori infection among the population of east coast of Borneo and explore the relationship between demographic factors, ethnicity and risk of H. pylori infection. Methods: This cross-sectional study enrolled 211 patients who underwent elective oesophagogastroduodenoscopy in 2017. Demographic data, endoscopic indications as well as the results of the mucosal biopsy were obtained and analysed from the endoscopy unit registry. Results: A total of 211 patients from 14 ethnic groups were enrolled in the study, most of were Chinese (28.4%), followed by Dusun (14.7%) and Songgai (13.7%). Overall, the period prevalence for 2017 was 44.5%. Multivariate logistic regression analysis showed an association between ethnicity and H. pylori. Bajau (adjusted odds ratio=5.612, P=0.005) and Dusun ethnic groups (adjusted odds ratio=7.359, P=0.001) were at a significantly higher risk of H. pylori infection compared to Chinese. However, the regression model only explained 11.6% (Cox & Snell Pseudo R2) of the prevalence of H. pylori infection. Conclusions: The period prevalence for 2017 was 44.5%, with certain indigenous ethnic groups having a higher risk than others. Clinicians should consider obtaining further history regarding the ethnic’s culture and dietary practice prior to starting H. pylori eradication therapy.http://www.johb.info/article.asp?issn=2773-0344;year=2022;volume=2;issue=1;spage=4;epage=4;aulast=Leehelicobacter pylori; prevalence; borneo; ethnicity |
| spellingShingle | Ooi-Cheng Lee Chung-Ket Lai Helicobacter pylori infection in a multi-ethnic population in east coast of Borneo, Malaysia: The effects of ethnicity One Health Bulletin helicobacter pylori; prevalence; borneo; ethnicity |
| title | Helicobacter pylori infection in a multi-ethnic population in east coast of Borneo, Malaysia: The effects of ethnicity |
| title_full | Helicobacter pylori infection in a multi-ethnic population in east coast of Borneo, Malaysia: The effects of ethnicity |
| title_fullStr | Helicobacter pylori infection in a multi-ethnic population in east coast of Borneo, Malaysia: The effects of ethnicity |
| title_full_unstemmed | Helicobacter pylori infection in a multi-ethnic population in east coast of Borneo, Malaysia: The effects of ethnicity |
| title_short | Helicobacter pylori infection in a multi-ethnic population in east coast of Borneo, Malaysia: The effects of ethnicity |
| title_sort | helicobacter pylori infection in a multi ethnic population in east coast of borneo malaysia the effects of ethnicity |
| topic | helicobacter pylori; prevalence; borneo; ethnicity |
| url | http://www.johb.info/article.asp?issn=2773-0344;year=2022;volume=2;issue=1;spage=4;epage=4;aulast=Lee |
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