Uric acid regulates α-synuclein transmission in Parkinsonian models

Uric acid regulates α-synuclein transmission in Parkinsonian models

Ample evidence demonstrates that α-synuclein (α-syn) has a critical role in the pathogenesis of Parkinson’s disease (PD) with evidence indicating that its propagation from one area of the brain to others may be the primary mechanism for disease progression. Uric acid (UA), a natural antioxidant, has...

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Bibliographic Details
Main Authors:	Yu Jin Shin, Yeon Ju Kim, Ji Eun Lee, Yi Seul Kim, Jung Wook Lee, HyeonJeong Kim, Jin Young Shin, Phil Hyu Lee
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-08-01
Series:	Frontiers in Aging Neuroscience
Subjects:	uric acid α-Syn transmission endocytosis Parkinson’s disease
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2023.1117491/full

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