A unique case of high‐grade myofibroblastic sarcoma initially presenting with oral symptoms
Abstract High‐grade myofibroblastic sarcoma is a rare mesenchymal tumor with a high recurrence and metastatic rate. Few cases of high‐grade myofibroblastic sarcomas have been reported. Herein, we report a rare case of undifferentiated, high‐grade myofibroblastic sarcoma with an unclear primary site,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-04-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.7218 |
| _version_ | 1797304152683970560 |
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| author | Takeshi Harada Takeshi Togawa Hiroki Miyamoto Yutaka Matsushita Yukimasa Hatachi |
| author_facet | Takeshi Harada Takeshi Togawa Hiroki Miyamoto Yutaka Matsushita Yukimasa Hatachi |
| author_sort | Takeshi Harada |
| collection | DOAJ |
| description | Abstract High‐grade myofibroblastic sarcoma is a rare mesenchymal tumor with a high recurrence and metastatic rate. Few cases of high‐grade myofibroblastic sarcomas have been reported. Herein, we report a rare case of undifferentiated, high‐grade myofibroblastic sarcoma with an unclear primary site, initially presenting with oral symptoms. High‐grade myofibroblastic sarcoma was diagnosed following an excisional biopsy of a gingival tumor. After this excisional biopsy, systemic imaging revealed multiple metastases in the tonsil, lung, liver, kidney, and eye. The patient underwent two cycles of chemotherapy (doxorubicin). During follow‐up, the tumor progressed rapidly and metastasized to the skin of the head and neck. The patient expired three months after the initial examination. |
| first_indexed | 2024-03-08T00:05:27Z |
| format | Article |
| id | doaj.art-a72bfb2363654280aa8b3ccfa3875d47 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-08T00:05:27Z |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-a72bfb2363654280aa8b3ccfa3875d472024-02-17T08:51:08ZengWileyClinical Case Reports2050-09042023-04-01114n/an/a10.1002/ccr3.7218A unique case of high‐grade myofibroblastic sarcoma initially presenting with oral symptomsTakeshi Harada0Takeshi Togawa1Hiroki Miyamoto2Yutaka Matsushita3Yukimasa Hatachi4Department of Oral and Maxillofacial Surgery Kansai Rosai Hospital Amagasaki Hyogo JapanDepartment of Oral and Maxillofacial Surgery Kansai Rosai Hospital Amagasaki Hyogo JapanDepartment of Oral and Maxillofacial Surgery Kansai Rosai Hospital Amagasaki Hyogo JapanDepartment of Oral and Maxillofacial Surgery Kansai Rosai Hospital Amagasaki Hyogo JapanDepartment of Medical Oncology Kansai Rosai Hospital Amagasaki Hyogo JapanAbstract High‐grade myofibroblastic sarcoma is a rare mesenchymal tumor with a high recurrence and metastatic rate. Few cases of high‐grade myofibroblastic sarcomas have been reported. Herein, we report a rare case of undifferentiated, high‐grade myofibroblastic sarcoma with an unclear primary site, initially presenting with oral symptoms. High‐grade myofibroblastic sarcoma was diagnosed following an excisional biopsy of a gingival tumor. After this excisional biopsy, systemic imaging revealed multiple metastases in the tonsil, lung, liver, kidney, and eye. The patient underwent two cycles of chemotherapy (doxorubicin). During follow‐up, the tumor progressed rapidly and metastasized to the skin of the head and neck. The patient expired three months after the initial examination.https://doi.org/10.1002/ccr3.7218chemotherapyimmunohistochemical stainingmultiple metastasesmyofibroblastic sarcoma |
| spellingShingle | Takeshi Harada Takeshi Togawa Hiroki Miyamoto Yutaka Matsushita Yukimasa Hatachi A unique case of high‐grade myofibroblastic sarcoma initially presenting with oral symptoms Clinical Case Reports chemotherapy immunohistochemical staining multiple metastases myofibroblastic sarcoma |
| title | A unique case of high‐grade myofibroblastic sarcoma initially presenting with oral symptoms |
| title_full | A unique case of high‐grade myofibroblastic sarcoma initially presenting with oral symptoms |
| title_fullStr | A unique case of high‐grade myofibroblastic sarcoma initially presenting with oral symptoms |
| title_full_unstemmed | A unique case of high‐grade myofibroblastic sarcoma initially presenting with oral symptoms |
| title_short | A unique case of high‐grade myofibroblastic sarcoma initially presenting with oral symptoms |
| title_sort | unique case of high grade myofibroblastic sarcoma initially presenting with oral symptoms |
| topic | chemotherapy immunohistochemical staining multiple metastases myofibroblastic sarcoma |
| url | https://doi.org/10.1002/ccr3.7218 |
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