MRI phantoms - are there alternatives to agar?
The suitability of different gelling agents as MRI phantoms was evaluated in terms of homogeneity, gel stability and reproducibility. Time and effort for preparation were also taken into account. The relaxation times of various gel compositions were estimated. Carbomer-980 and Carbopol-974P were det...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3734012?pdf=render |
| _version_ | 1818387671772299264 |
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| author | Alexandra Hellerbach Verena Schuster Andreas Jansen Jens Sommer |
| author_facet | Alexandra Hellerbach Verena Schuster Andreas Jansen Jens Sommer |
| author_sort | Alexandra Hellerbach |
| collection | DOAJ |
| description | The suitability of different gelling agents as MRI phantoms was evaluated in terms of homogeneity, gel stability and reproducibility. Time and effort for preparation were also taken into account. The relaxation times of various gel compositions were estimated. Carbomer-980 and Carbopol-974P were determined to be promising novel phantom materials. These gelling agents are readily available, inexpensive and easy to handle given that thermal treatment is not required. Furthermore, the viscoelasticity of their polymer network is pH-dependent. With such characteristics, it was even possible to embed sensitive objects and retrieve them after testing. This was demonstrated with a fiber phantom for Diffusion Weighted MRI applications. Since Carbomer-980 and Carbopol-974P are non-hazardous, they are also suitable for multimodal setups (e.g., MRI as well as ultrasonic imaging). |
| first_indexed | 2024-12-14T04:13:39Z |
| format | Article |
| id | doaj.art-a72c21645730489c898610e2a2da96d5 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T04:13:39Z |
| publishDate | 2013-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-a72c21645730489c898610e2a2da96d52022-12-21T23:17:36ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0188e7034310.1371/journal.pone.0070343MRI phantoms - are there alternatives to agar?Alexandra HellerbachVerena SchusterAndreas JansenJens SommerThe suitability of different gelling agents as MRI phantoms was evaluated in terms of homogeneity, gel stability and reproducibility. Time and effort for preparation were also taken into account. The relaxation times of various gel compositions were estimated. Carbomer-980 and Carbopol-974P were determined to be promising novel phantom materials. These gelling agents are readily available, inexpensive and easy to handle given that thermal treatment is not required. Furthermore, the viscoelasticity of their polymer network is pH-dependent. With such characteristics, it was even possible to embed sensitive objects and retrieve them after testing. This was demonstrated with a fiber phantom for Diffusion Weighted MRI applications. Since Carbomer-980 and Carbopol-974P are non-hazardous, they are also suitable for multimodal setups (e.g., MRI as well as ultrasonic imaging).http://europepmc.org/articles/PMC3734012?pdf=render |
| spellingShingle | Alexandra Hellerbach Verena Schuster Andreas Jansen Jens Sommer MRI phantoms - are there alternatives to agar? PLoS ONE |
| title | MRI phantoms - are there alternatives to agar? |
| title_full | MRI phantoms - are there alternatives to agar? |
| title_fullStr | MRI phantoms - are there alternatives to agar? |
| title_full_unstemmed | MRI phantoms - are there alternatives to agar? |
| title_short | MRI phantoms - are there alternatives to agar? |
| title_sort | mri phantoms are there alternatives to agar |
| url | http://europepmc.org/articles/PMC3734012?pdf=render |
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