Colorectal Liver Metastases: A Literature Review of Viable Surgical Options with a Special Focus on Microwave Liver Thermal Ablation and Mini-Invasive Approach
Colorectal cancer (CRC) is the third most common tumor worldwide and it is characterized in 20–30% of cases by liver involvement, which strongly affects the long-term patient outcome. There are many available therapies for liver colorectal metastases (CRLMs); the current standard of care is represen...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/13/1/33 |
| _version_ | 1797440149954494464 |
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| author | Michele Finotti Francesco Enrico D’Amico Maurizio Romano Marco Brizzolari Michele Scopelliti Giacomo Zanus |
| author_facet | Michele Finotti Francesco Enrico D’Amico Maurizio Romano Marco Brizzolari Michele Scopelliti Giacomo Zanus |
| author_sort | Michele Finotti |
| collection | DOAJ |
| description | Colorectal cancer (CRC) is the third most common tumor worldwide and it is characterized in 20–30% of cases by liver involvement, which strongly affects the long-term patient outcome. There are many available therapies for liver colorectal metastases (CRLMs); the current standard of care is represented by liver resection, and when feasible, associated with systemic chemotherapy. Microwave thermal ablation (MWA) is a viable option in unresectable patients or to achieve treatment with a parenchymal spearing approach. A literature review was performed for studies published between January 2000 and July 2022 through a database search using PUBMED/Medline and the Cochrane Collaboration Library with the following MeSH search terms and keywords: microwave, ablation, liver metastases, colorectal neoplasm, and colon liver rectal metastases. The recurrence rate and overall patients’ survival were evaluated, showing that laparoscopic MWA is safe and effective to treat CRLMs when resection is not feasible, or a major hepatectomy in fragile patients is necessary. Considering the low morbidity of this procedure, it is a viable option to treat patients with recurrent diseases in the era of effective chemotherapy and multimodal treatments. |
| first_indexed | 2024-03-09T12:02:56Z |
| format | Article |
| id | doaj.art-a72cf7eb74e7459da4c9568ff9bbec4f |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-09T12:02:56Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-a72cf7eb74e7459da4c9568ff9bbec4f2023-11-30T23:01:13ZengMDPI AGJournal of Personalized Medicine2075-44262022-12-011313310.3390/jpm13010033Colorectal Liver Metastases: A Literature Review of Viable Surgical Options with a Special Focus on Microwave Liver Thermal Ablation and Mini-Invasive ApproachMichele Finotti0Francesco Enrico D’Amico1Maurizio Romano2Marco Brizzolari3Michele Scopelliti4Giacomo Zanus54th Surgery Unit, Regional Hospital Treviso, University of Padua, DISCOG, 31100 Padua, ItalySecond General Surgical Unit, Padova Teaching Hospital, 35128 Padua, Italy4th Surgery Unit, Regional Hospital Treviso, University of Padua, DISCOG, 31100 Padua, Italy4th Surgery Unit, Regional Hospital Treviso, University of Padua, DISCOG, 31100 Padua, Italy4th Surgery Unit, Regional Hospital Treviso, University of Padua, DISCOG, 31100 Padua, Italy4th Surgery Unit, Regional Hospital Treviso, University of Padua, DISCOG, 31100 Padua, ItalyColorectal cancer (CRC) is the third most common tumor worldwide and it is characterized in 20–30% of cases by liver involvement, which strongly affects the long-term patient outcome. There are many available therapies for liver colorectal metastases (CRLMs); the current standard of care is represented by liver resection, and when feasible, associated with systemic chemotherapy. Microwave thermal ablation (MWA) is a viable option in unresectable patients or to achieve treatment with a parenchymal spearing approach. A literature review was performed for studies published between January 2000 and July 2022 through a database search using PUBMED/Medline and the Cochrane Collaboration Library with the following MeSH search terms and keywords: microwave, ablation, liver metastases, colorectal neoplasm, and colon liver rectal metastases. The recurrence rate and overall patients’ survival were evaluated, showing that laparoscopic MWA is safe and effective to treat CRLMs when resection is not feasible, or a major hepatectomy in fragile patients is necessary. Considering the low morbidity of this procedure, it is a viable option to treat patients with recurrent diseases in the era of effective chemotherapy and multimodal treatments.https://www.mdpi.com/2075-4426/13/1/33liver metastasesmicrowave ablationthermal liver ablationmini invase liver surgerylaparoscopic liver ablation |
| spellingShingle | Michele Finotti Francesco Enrico D’Amico Maurizio Romano Marco Brizzolari Michele Scopelliti Giacomo Zanus Colorectal Liver Metastases: A Literature Review of Viable Surgical Options with a Special Focus on Microwave Liver Thermal Ablation and Mini-Invasive Approach Journal of Personalized Medicine liver metastases microwave ablation thermal liver ablation mini invase liver surgery laparoscopic liver ablation |
| title | Colorectal Liver Metastases: A Literature Review of Viable Surgical Options with a Special Focus on Microwave Liver Thermal Ablation and Mini-Invasive Approach |
| title_full | Colorectal Liver Metastases: A Literature Review of Viable Surgical Options with a Special Focus on Microwave Liver Thermal Ablation and Mini-Invasive Approach |
| title_fullStr | Colorectal Liver Metastases: A Literature Review of Viable Surgical Options with a Special Focus on Microwave Liver Thermal Ablation and Mini-Invasive Approach |
| title_full_unstemmed | Colorectal Liver Metastases: A Literature Review of Viable Surgical Options with a Special Focus on Microwave Liver Thermal Ablation and Mini-Invasive Approach |
| title_short | Colorectal Liver Metastases: A Literature Review of Viable Surgical Options with a Special Focus on Microwave Liver Thermal Ablation and Mini-Invasive Approach |
| title_sort | colorectal liver metastases a literature review of viable surgical options with a special focus on microwave liver thermal ablation and mini invasive approach |
| topic | liver metastases microwave ablation thermal liver ablation mini invase liver surgery laparoscopic liver ablation |
| url | https://www.mdpi.com/2075-4426/13/1/33 |
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