Impact of alcohol use on thyroid function
Alcohol is one of the commonest illicit psychoactive substances consumed globally and is the world′s third largest risk factor for disease and disability. It has been reported to have multiple effects on the hypothalamo-pituitary-thyroid axis and the functioning of the thyroid gland. It has been rep...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2013-01-01
|
| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=4;spage=580;epage=587;aulast=Balhara |
| _version_ | 1811203218381733888 |
|---|---|
| author | Yatan Pal Singh Balhara Koushik Sinha Deb |
| author_facet | Yatan Pal Singh Balhara Koushik Sinha Deb |
| author_sort | Yatan Pal Singh Balhara |
| collection | DOAJ |
| description | Alcohol is one of the commonest illicit psychoactive substances consumed globally and is the world′s third largest risk factor for disease and disability. It has been reported to have multiple effects on the hypothalamo-pituitary-thyroid axis and the functioning of the thyroid gland. It has been reported to cause direct suppression of thyroid function by cellular toxicity, and indirect suppression by blunting thyrotropin-releasing hormone response. It causes a decrease of peripheral thyroid hormones during chronic use and in withdrawal. Alcohol use may also confer some protective effect against thyroid nodularity, goiter, and thyroid cancer. This article presents a review of the clinically relevant effects of alcohol on the functioning of the thyroid gland and also discusses the effect of medication used in treatment of alcohol dependence on thyroid function. |
| first_indexed | 2024-04-12T02:51:04Z |
| format | Article |
| id | doaj.art-a72d22baddd94e288dd577f32a8480d0 |
| institution | Directory Open Access Journal |
| issn | 2230-8210 2230-9500 |
| language | English |
| last_indexed | 2024-04-12T02:51:04Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-a72d22baddd94e288dd577f32a8480d02022-12-22T03:50:59ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002013-01-0117458058710.4103/2230-8210.113724Impact of alcohol use on thyroid functionYatan Pal Singh BalharaKoushik Sinha DebAlcohol is one of the commonest illicit psychoactive substances consumed globally and is the world′s third largest risk factor for disease and disability. It has been reported to have multiple effects on the hypothalamo-pituitary-thyroid axis and the functioning of the thyroid gland. It has been reported to cause direct suppression of thyroid function by cellular toxicity, and indirect suppression by blunting thyrotropin-releasing hormone response. It causes a decrease of peripheral thyroid hormones during chronic use and in withdrawal. Alcohol use may also confer some protective effect against thyroid nodularity, goiter, and thyroid cancer. This article presents a review of the clinically relevant effects of alcohol on the functioning of the thyroid gland and also discusses the effect of medication used in treatment of alcohol dependence on thyroid function.http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=4;spage=580;epage=587;aulast=BalharaAlcoholhypothalamus-pituitary-thyroid axisthyroidtobacco |
| spellingShingle | Yatan Pal Singh Balhara Koushik Sinha Deb Impact of alcohol use on thyroid function Indian Journal of Endocrinology and Metabolism Alcohol hypothalamus-pituitary-thyroid axis thyroid tobacco |
| title | Impact of alcohol use on thyroid function |
| title_full | Impact of alcohol use on thyroid function |
| title_fullStr | Impact of alcohol use on thyroid function |
| title_full_unstemmed | Impact of alcohol use on thyroid function |
| title_short | Impact of alcohol use on thyroid function |
| title_sort | impact of alcohol use on thyroid function |
| topic | Alcohol hypothalamus-pituitary-thyroid axis thyroid tobacco |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=4;spage=580;epage=587;aulast=Balhara |
| work_keys_str_mv | AT yatanpalsinghbalhara impactofalcoholuseonthyroidfunction AT koushiksinhadeb impactofalcoholuseonthyroidfunction |