The Age-Related Perfusion Pattern Measured With Arterial Spin Labeling MRI in Healthy Subjects

The Age-Related Perfusion Pattern Measured With Arterial Spin Labeling MRI in Healthy Subjects

Aim: To analyze age-related cerebral blood flow (CBF) using arterial spin labeling (ASL) MRI in healthy subjects with multivariate principal component analysis (PCA).Methods: 50 healthy subjects (mean age 45.8 ± 18.5 years, range 21–85) had 3D structural MRI and pseudo-continuous ASL MRI at resting...

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Bibliographic Details
Main Authors: Nan Zhang, Marc L. Gordon, Yilong Ma, Bradley Chi, Jesus J. Gomar, Shichun Peng, Peter B. Kingsley, David Eidelberg, Terry E. Goldberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
arterial spin labeling
cerebral blood flow
aging
principal component analysis
scaled subprofile model
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00214/full

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