Growth factor-enriched autologous plasma improves wound healing after surgical debridement in odontogenic necrotizing fasciitis: a case report
<p>Abstract</p> <p>Background</p> <p>Odontogenic necrotizing fasciitis of the neck is a fulminant infection of odontogenic origin that quickly spreads along the fascial planes and results in necrosis of the affected tissues. It is usually polymicrobial, occurs frequentl...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-03-01
|
| Series: | Journal of Medical Case Reports |
| Online Access: | http://www.jmedicalcasereports.com/content/5/1/98 |
| _version_ | 1811277467159101440 |
|---|---|
| author | Martinez-Fong Daniel Leon-Chavez Alicia Martinez-Aguilar Nora Ramirez-Melgoza Jorge Lopez-Fernandez Rubi Gonzalez-Barrios Juan |
| author_facet | Martinez-Fong Daniel Leon-Chavez Alicia Martinez-Aguilar Nora Ramirez-Melgoza Jorge Lopez-Fernandez Rubi Gonzalez-Barrios Juan |
| author_sort | Martinez-Fong Daniel |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Odontogenic necrotizing fasciitis of the neck is a fulminant infection of odontogenic origin that quickly spreads along the fascial planes and results in necrosis of the affected tissues. It is usually polymicrobial, occurs frequently in immunocompromised patients, and has a high mortality rate.</p> <p>Case presentation</p> <p>A 69-year old Mexican male had a pain in the maxillar right-canine region and a swelling of the submental and submandibular regions. Our examination revealed local pain, tachycardia, hyperthermia (39°C), and the swelling of bilateral submental and submandibular regions, which also were erythematous, hyperthermic, crepitant, and with a positive Godet sign. Mobility and third-degree caries were seen in the right mandibular canine. Bacteriological cultures isolated <it>streptococcus pyogenes </it>and <it>staphylococcus aureus</it>. The histopathological diagnosis was odontogenic necrotizing fasciitis of the submental and submandibular regions. The initial treatment was surgical debridement and the administration of antibiotics. After cultures were negative, the surgical wound was treated with a growth factor-enriched autologous plasma eight times every third day until complete healing occurred.</p> <p>Conclusions</p> <p>The treatment with a growth factor-enriched autologous plasma caused a rapid healing of an extensive surgical wound in a patient with odontogenic necrotizing fasciitis. The benefits were rapid tissue regeneration, an aesthetic and a functional scar, and the avoidance of further surgery and possible complications.</p> |
| first_indexed | 2024-04-13T00:17:06Z |
| format | Article |
| id | doaj.art-a739265509cb4bc1b43f772790890880 |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-04-13T00:17:06Z |
| publishDate | 2011-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-a739265509cb4bc1b43f7727908908802022-12-22T03:10:55ZengBMCJournal of Medical Case Reports1752-19472011-03-01519810.1186/1752-1947-5-98Growth factor-enriched autologous plasma improves wound healing after surgical debridement in odontogenic necrotizing fasciitis: a case reportMartinez-Fong DanielLeon-Chavez AliciaMartinez-Aguilar NoraRamirez-Melgoza JorgeLopez-Fernandez RubiGonzalez-Barrios Juan<p>Abstract</p> <p>Background</p> <p>Odontogenic necrotizing fasciitis of the neck is a fulminant infection of odontogenic origin that quickly spreads along the fascial planes and results in necrosis of the affected tissues. It is usually polymicrobial, occurs frequently in immunocompromised patients, and has a high mortality rate.</p> <p>Case presentation</p> <p>A 69-year old Mexican male had a pain in the maxillar right-canine region and a swelling of the submental and submandibular regions. Our examination revealed local pain, tachycardia, hyperthermia (39°C), and the swelling of bilateral submental and submandibular regions, which also were erythematous, hyperthermic, crepitant, and with a positive Godet sign. Mobility and third-degree caries were seen in the right mandibular canine. Bacteriological cultures isolated <it>streptococcus pyogenes </it>and <it>staphylococcus aureus</it>. The histopathological diagnosis was odontogenic necrotizing fasciitis of the submental and submandibular regions. The initial treatment was surgical debridement and the administration of antibiotics. After cultures were negative, the surgical wound was treated with a growth factor-enriched autologous plasma eight times every third day until complete healing occurred.</p> <p>Conclusions</p> <p>The treatment with a growth factor-enriched autologous plasma caused a rapid healing of an extensive surgical wound in a patient with odontogenic necrotizing fasciitis. The benefits were rapid tissue regeneration, an aesthetic and a functional scar, and the avoidance of further surgery and possible complications.</p>http://www.jmedicalcasereports.com/content/5/1/98 |
| spellingShingle | Martinez-Fong Daniel Leon-Chavez Alicia Martinez-Aguilar Nora Ramirez-Melgoza Jorge Lopez-Fernandez Rubi Gonzalez-Barrios Juan Growth factor-enriched autologous plasma improves wound healing after surgical debridement in odontogenic necrotizing fasciitis: a case report Journal of Medical Case Reports |
| title | Growth factor-enriched autologous plasma improves wound healing after surgical debridement in odontogenic necrotizing fasciitis: a case report |
| title_full | Growth factor-enriched autologous plasma improves wound healing after surgical debridement in odontogenic necrotizing fasciitis: a case report |
| title_fullStr | Growth factor-enriched autologous plasma improves wound healing after surgical debridement in odontogenic necrotizing fasciitis: a case report |
| title_full_unstemmed | Growth factor-enriched autologous plasma improves wound healing after surgical debridement in odontogenic necrotizing fasciitis: a case report |
| title_short | Growth factor-enriched autologous plasma improves wound healing after surgical debridement in odontogenic necrotizing fasciitis: a case report |
| title_sort | growth factor enriched autologous plasma improves wound healing after surgical debridement in odontogenic necrotizing fasciitis a case report |
| url | http://www.jmedicalcasereports.com/content/5/1/98 |
| work_keys_str_mv | AT martinezfongdaniel growthfactorenrichedautologousplasmaimproveswoundhealingaftersurgicaldebridementinodontogenicnecrotizingfasciitisacasereport AT leonchavezalicia growthfactorenrichedautologousplasmaimproveswoundhealingaftersurgicaldebridementinodontogenicnecrotizingfasciitisacasereport AT martinezaguilarnora growthfactorenrichedautologousplasmaimproveswoundhealingaftersurgicaldebridementinodontogenicnecrotizingfasciitisacasereport AT ramirezmelgozajorge growthfactorenrichedautologousplasmaimproveswoundhealingaftersurgicaldebridementinodontogenicnecrotizingfasciitisacasereport AT lopezfernandezrubi growthfactorenrichedautologousplasmaimproveswoundhealingaftersurgicaldebridementinodontogenicnecrotizingfasciitisacasereport AT gonzalezbarriosjuan growthfactorenrichedautologousplasmaimproveswoundhealingaftersurgicaldebridementinodontogenicnecrotizingfasciitisacasereport |