An integrated proteome and transcriptome of B cell maturation defines poised activation states of transitional and mature B cells

Abstract During B cell maturation, transitional and mature B cells acquire cell-intrinsic features that determine their ability to exit quiescence and mount effective immune responses. Here we use label-free proteomics to quantify the proteome of B cell subsets from the mouse spleen and map the diff...

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Bibliographic Details
Main Authors: Fiamma Salerno, Andrew J. M. Howden, Louise S. Matheson, Özge Gizlenci, Michael Screen, Holger Lingel, Monika C. Brunner-Weinzierl, Martin Turner
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40621-2

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