In Vivo Evidence of Blue LED Light Photobiomodulation

The following study investigated the effects of blue LED light (410–430 nm) on wound healing in mice with superficial and full-thickness skin wounds. The wounds were treated with blue LED light (20.6 J/cm<sup>2</sup>, 30 s), and biopsies were collected over 6 days. Results showed modulat...

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Main Authors: Giada Magni, Francesca Tatini, Michele Rossi, Gaetano de Siena, Riccardo Cicchi, Francesco S. Pavone, Stefano Bacci, Francesca Rossi
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Medical Sciences Forum
Subjects:
Online Access:https://www.mdpi.com/2673-9992/21/1/6
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author Giada Magni
Francesca Tatini
Michele Rossi
Gaetano de Siena
Riccardo Cicchi
Francesco S. Pavone
Stefano Bacci
Francesca Rossi
author_facet Giada Magni
Francesca Tatini
Michele Rossi
Gaetano de Siena
Riccardo Cicchi
Francesco S. Pavone
Stefano Bacci
Francesca Rossi
author_sort Giada Magni
collection DOAJ
description The following study investigated the effects of blue LED light (410–430 nm) on wound healing in mice with superficial and full-thickness skin wounds. The wounds were treated with blue LED light (20.6 J/cm<sup>2</sup>, 30 s), and biopsies were collected over 6 days. Results showed modulation of cytokine release, increased number of granulocytes and mast cells, increased density of vessels with mast cells expressing platelet-derived growth factor, and improved collagen deposition compared to untreated wounds. The study concluded that blue light leads to faster and more effective wound healing and improved skin morphology.
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spelling doaj.art-a73ba297c114409486f5893716f0bd912023-12-22T14:28:42ZengMDPI AGMedical Sciences Forum2673-99922023-03-01211610.3390/ECB2023-14287In Vivo Evidence of Blue LED Light PhotobiomodulationGiada Magni0Francesca Tatini1Michele Rossi2Gaetano de Siena3Riccardo Cicchi4Francesco S. Pavone5Stefano Bacci6Francesca Rossi7Consiglio Nazionale delle Ricerche, Istituto di Fisica Applicata “Nello Carrara”, (CNR-IFAC), 50019 Florence, ItalyConsiglio Nazionale delle Ricerche, Istituto di Fisica Applicata “Nello Carrara”, (CNR-IFAC), 50019 Florence, ItalyConsiglio Nazionale delle Ricerche, Istituto di Fisica Applicata “Nello Carrara”, (CNR-IFAC), 50019 Florence, ItalyConsiglio Nazionale delle Ricerche, Istituto di Fisica Applicata “Nello Carrara”, (CNR-IFAC), 50019 Florence, ItalyConsiglio Nazionale delle Ricerche, Istituto Nazionale di Ottica, (CNR-INO), 50019 Florence, ItalyEuropean Laboratory for Non-Linear Spectroscopy (LENS), Università di Firenze, 50019 Florence, ItalyConsiglio Nazionale delle Ricerche, Istituto di Fisica Applicata “Nello Carrara”, (CNR-IFAC), 50019 Florence, ItalyConsiglio Nazionale delle Ricerche, Istituto di Fisica Applicata “Nello Carrara”, (CNR-IFAC), 50019 Florence, ItalyThe following study investigated the effects of blue LED light (410–430 nm) on wound healing in mice with superficial and full-thickness skin wounds. The wounds were treated with blue LED light (20.6 J/cm<sup>2</sup>, 30 s), and biopsies were collected over 6 days. Results showed modulation of cytokine release, increased number of granulocytes and mast cells, increased density of vessels with mast cells expressing platelet-derived growth factor, and improved collagen deposition compared to untreated wounds. The study concluded that blue light leads to faster and more effective wound healing and improved skin morphology.https://www.mdpi.com/2673-9992/21/1/6photobiomodulationwound healingblue LED lightin vivo model
spellingShingle Giada Magni
Francesca Tatini
Michele Rossi
Gaetano de Siena
Riccardo Cicchi
Francesco S. Pavone
Stefano Bacci
Francesca Rossi
In Vivo Evidence of Blue LED Light Photobiomodulation
Medical Sciences Forum
photobiomodulation
wound healing
blue LED light
in vivo model
title In Vivo Evidence of Blue LED Light Photobiomodulation
title_full In Vivo Evidence of Blue LED Light Photobiomodulation
title_fullStr In Vivo Evidence of Blue LED Light Photobiomodulation
title_full_unstemmed In Vivo Evidence of Blue LED Light Photobiomodulation
title_short In Vivo Evidence of Blue LED Light Photobiomodulation
title_sort in vivo evidence of blue led light photobiomodulation
topic photobiomodulation
wound healing
blue LED light
in vivo model
url https://www.mdpi.com/2673-9992/21/1/6
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AT gaetanodesiena invivoevidenceofblueledlightphotobiomodulation
AT riccardocicchi invivoevidenceofblueledlightphotobiomodulation
AT francescospavone invivoevidenceofblueledlightphotobiomodulation
AT stefanobacci invivoevidenceofblueledlightphotobiomodulation
AT francescarossi invivoevidenceofblueledlightphotobiomodulation