Contribution to the phytochemical study and biological activity of plants of Cuban flora
Interest in natural products as a source for innovation in drug discovery and agrochemicals is still growing worldwide. Natural products, whose immense diversity has been appreciated for many years, may become in a rich source of novel chemical structures. Our country is a rich source of both biolog...
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| Format: | Article |
| Language: | English |
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Elfos Scientiae
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| Series: | Biotecnología Aplicada |
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| Online Access: | http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000400010&lng=en&tlng=en |
| _version_ | 1818157969461739520 |
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| author | Clara Nogueiras Iraida Spengler José O Guerra Yarelys Ortiz Susana Torres Trina H García Carlos R Romeu Erik L Regalado Telce A González Wilmer H Perera Rodney Lacret |
| author_facet | Clara Nogueiras Iraida Spengler José O Guerra Yarelys Ortiz Susana Torres Trina H García Carlos R Romeu Erik L Regalado Telce A González Wilmer H Perera Rodney Lacret |
| author_sort | Clara Nogueiras |
| collection | DOAJ |
| description | Interest in natural products as a source for innovation in drug discovery and agrochemicals is still growing worldwide. Natural products, whose immense diversity has been appreciated for many years, may become in a rich source of novel chemical structures. Our country is a rich source of both biological and chemical diversity which may be useful as a source of novel chemical structures. Even when natural products have been used as medicinal agents for many years in Cuba, their use as agrochemicals are still limited. Thus, the present review focuses on recent advances in the studies on natural products performed by the "Centro de Estudios de Productos Naturales, CEPN" during the past ten years, highlighting on those with potential use as biomedical and agrochemicals. 15 plant species were studied; Agave brittoniana Trel. Subsp. brachypus A Álvarez de Zayas (Agavaceae); Juniperus barbadensis L. var. Lucayana (Britt.) RP Adams (Cupressaceae); Melia azedarach Linn. (Meliaceae); Tectona grandis Linn. f. (Lamiaceae); Lantana camara Linn. (Verbenaceae); Lantana trifolia Cham. (Verbenaceae); Citrus sinensis (Linn.) Osbeck cv Valencia (Rutaceae); Maytenus buxifolia (A Rich) Griseb (Celastraceae); Maytenus elaeodendroides Griseb (Celastraceae); Maytenus urquiolae B Mory (Celastraceae); Solanum americanum W. Mill (Solanaceae); Thalassia testudinum Kon. (Hydrocharitaceae); Sesbania rostrata Bremek & Oberm (Fabaceae); Pluchea carolinensis G Don (Asteraceae) and Ageratina havanensis (HB & K) RM King & Robinson (Asteraceae). By means of a bio-guided fractionation, isolated structures as well as semi-purified fractions were assayed as antioxidant, antiparasitic, antibiotic, insecticides, antifungal, and skin regenerating and healing effects. The strategy employed allows us to discover novel secondary metabolites with potential for industrial development as pharmaceuticals and/or agrochemicals. Besides, in addition to the goal of discovering new bioactive agents, the presence of unique bioactive compounds notably contribute to increase the knowledge of plant species in Cuba. |
| first_indexed | 2024-12-11T15:22:38Z |
| format | Article |
| id | doaj.art-a73eb34f0fa541fb8fea05ed1b0aeedf |
| institution | Directory Open Access Journal |
| issn | 1027-2852 |
| language | English |
| last_indexed | 2024-12-11T15:22:38Z |
| publisher | Elfos Scientiae |
| record_format | Article |
| series | Biotecnología Aplicada |
| spelling | doaj.art-a73eb34f0fa541fb8fea05ed1b0aeedf2022-12-22T01:00:20ZengElfos ScientiaeBiotecnología Aplicada1027-2852274314318S1027-28522010000400010Contribution to the phytochemical study and biological activity of plants of Cuban floraClara Nogueiras0Iraida Spengler1José O Guerra2Yarelys Ortiz3Susana Torres4Trina H García5Carlos R Romeu6Erik L Regalado7Telce A González8Wilmer H Perera9Rodney Lacret10Universidad de la HabanaUniversidad de la HabanaUniversidad Central Marta Abreu de las VillasInstituto de Investigaciones Fundamentales de la Agricultura Tropical, INIFATUniversidad de la HabanaUniversidad de la HabanaInstituto de Sanidad Vegetal, INISAVCentro de Bioproductos Marinos, CEBIMARInstituto de Investigaciones del ArrozCITMAUniversidad de la HabanaInterest in natural products as a source for innovation in drug discovery and agrochemicals is still growing worldwide. Natural products, whose immense diversity has been appreciated for many years, may become in a rich source of novel chemical structures. Our country is a rich source of both biological and chemical diversity which may be useful as a source of novel chemical structures. Even when natural products have been used as medicinal agents for many years in Cuba, their use as agrochemicals are still limited. Thus, the present review focuses on recent advances in the studies on natural products performed by the "Centro de Estudios de Productos Naturales, CEPN" during the past ten years, highlighting on those with potential use as biomedical and agrochemicals. 15 plant species were studied; Agave brittoniana Trel. Subsp. brachypus A Álvarez de Zayas (Agavaceae); Juniperus barbadensis L. var. Lucayana (Britt.) RP Adams (Cupressaceae); Melia azedarach Linn. (Meliaceae); Tectona grandis Linn. f. (Lamiaceae); Lantana camara Linn. (Verbenaceae); Lantana trifolia Cham. (Verbenaceae); Citrus sinensis (Linn.) Osbeck cv Valencia (Rutaceae); Maytenus buxifolia (A Rich) Griseb (Celastraceae); Maytenus elaeodendroides Griseb (Celastraceae); Maytenus urquiolae B Mory (Celastraceae); Solanum americanum W. Mill (Solanaceae); Thalassia testudinum Kon. (Hydrocharitaceae); Sesbania rostrata Bremek & Oberm (Fabaceae); Pluchea carolinensis G Don (Asteraceae) and Ageratina havanensis (HB & K) RM King & Robinson (Asteraceae). By means of a bio-guided fractionation, isolated structures as well as semi-purified fractions were assayed as antioxidant, antiparasitic, antibiotic, insecticides, antifungal, and skin regenerating and healing effects. The strategy employed allows us to discover novel secondary metabolites with potential for industrial development as pharmaceuticals and/or agrochemicals. Besides, in addition to the goal of discovering new bioactive agents, the presence of unique bioactive compounds notably contribute to increase the knowledge of plant species in Cuba.http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000400010&lng=en&tlng=enbioactivity of cuban plantsflavonoidssaponins and steroidal sapogeninsterpenoids and triterpenoidsquinones and phenolic compounds |
| spellingShingle | Clara Nogueiras Iraida Spengler José O Guerra Yarelys Ortiz Susana Torres Trina H García Carlos R Romeu Erik L Regalado Telce A González Wilmer H Perera Rodney Lacret Contribution to the phytochemical study and biological activity of plants of Cuban flora Biotecnología Aplicada bioactivity of cuban plants flavonoids saponins and steroidal sapogenins terpenoids and triterpenoids quinones and phenolic compounds |
| title | Contribution to the phytochemical study and biological activity of plants of Cuban flora |
| title_full | Contribution to the phytochemical study and biological activity of plants of Cuban flora |
| title_fullStr | Contribution to the phytochemical study and biological activity of plants of Cuban flora |
| title_full_unstemmed | Contribution to the phytochemical study and biological activity of plants of Cuban flora |
| title_short | Contribution to the phytochemical study and biological activity of plants of Cuban flora |
| title_sort | contribution to the phytochemical study and biological activity of plants of cuban flora |
| topic | bioactivity of cuban plants flavonoids saponins and steroidal sapogenins terpenoids and triterpenoids quinones and phenolic compounds |
| url | http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000400010&lng=en&tlng=en |
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