Immunogenicity, Efficacy, and Safety of a Novel Synthetic Microparticle Pre-Erythrocytic Malaria Vaccine in Multiple Host Species

Immunogenicity, Efficacy, and Safety of a Novel Synthetic Microparticle Pre-Erythrocytic Malaria Vaccine in Multiple Host Species

We previously reported a protective antibody response in mice immunized with synthetic microparticle vaccines made using layer-by-layer fabrication (LbL-MP) and containing the conserved T1BT* epitopes from the <i>P. falciparum</i> circumsporozoite protein. To further optimize the vaccine...

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Bibliographic Details
Main Authors: Thomas J. Powell, Jie Tang, Robert Mitchell, Mary E. DeRome, Andrea Jacobs, Naveen Palath, Edwin Cardenas, Michelle Yorke, James G. Boyd, Stephen A. Kaba, Elizabeth Nardin
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Vaccines
Subjects:
malaria vaccine
microparticle
non-human primate
peptide
sporozoite
Online Access:https://www.mdpi.com/2076-393X/11/12/1789

Internet

https://www.mdpi.com/2076-393X/11/12/1789

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