A serological biomarker of type I collagen degradation is related to a more severe, high neutrophilic, obese asthma subtype

A serological biomarker of type I collagen degradation is related to a more severe, high neutrophilic, obese asthma subtype

Abstract Background Asthma is a heterogeneous disease; therefore, biomarkers that can assist in the identification of subtypes and direct therapy are highly desirable. Asthma is a chronic inflammatory disease that leads to changes in the extracellular matrix (ECM) by matrix metalloproteinases (MMPs)...

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Main Authors: Sarah Rank Rønnow, Jannie Marie Bülow Sand, Line Mærsk Staunstrup, Thomas Bahmer, Michael Wegmann, Lars Lunding, Janette Burgess, Klaus Rabe, Grith Lykke Sorensen, Oliver Fuchs, Erika V. Mutius, Gesine Hansen, Matthias Volkmar Kopp, Morten Karsdal, Diana Julie Leeming, Markus Weckmann, the ALLIANCE Study Group as part of the German Center of Lung Research (DZL)
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Asthma Research and Practice
Online Access:https://doi.org/10.1186/s40733-022-00084-6

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