Megakaryocyte apoptosis in immune thrombocytopenia

Megakaryocyte apoptosis in immune thrombocytopenia

The mechanisms of platelet underproduction in immune thrombocytopenia (ITP) remain unknown. While the number of megakaryocytes is normal or increased in ITP bone marrow, further studies of megakaryocyte integrity are needed. Megakaryocytes are responsible for the production of platelets in the bone...

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Bibliographic Details
Main Authors: John R. Vrbensky, Ishac Nazy, Lisa J. Toltl, Catherine Ross, Nikola Ivetic, James W. Smith, John G. Kelton, Donald M. Arnold
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Platelets
Subjects:
apoptosis
autoimmune disease
bone marrow pathology
itp
megakaryocytes
Online Access:http://dx.doi.org/10.1080/09537104.2018.1475637

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