Effects of deficient mismatch repair on the prognosis of patients with stage II and stage III colon cancer during different postoperative periods

Effects of deficient mismatch repair on the prognosis of patients with stage II and stage III colon cancer during different postoperative periods

Abstract Background We evaluated the prognostic role of deficient mismatch repair (dMMR) systems in stage II and stage III colon cancer patients during different postoperative periods. We also assessed whether patients aged ≥75 could benefit from chemotherapy. Methods This retrospective study was co...

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Bibliographic Details
Main Authors: Chunze Zhang, Yixiang Zhan, Kemin Ni, Zhaoce Liu, Ran Xin, Qiurong Han, Guoxun Li, Hangyu Ping, Yaohong Liu, Xuanzhu Zhao, Wanting Wang, Suying Yan, Jing Sun, Qinghuai Zhang, Guihua Wang, Zili Zhang, Xipeng Zhang, Xia Hu
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Cancer
Subjects:
Colon cancer
Adjuvant chemotherapy
Mismatch repair
Multicenter study
Online Access:https://doi.org/10.1186/s12885-022-10266-3

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