Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus.
We report photoacoustic and ultrasonic endoscopic images of two intact rabbit esophagi. To investigate the esophageal lumen structure and microvasculature, we performed in vivo and ex vivo imaging studies using a 3.8-mm diameter photoacoustic endoscope and correlated the images with histology. Sever...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4398324?pdf=render |
| _version_ | 1818028897226194944 |
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| author | Joon Mo Yang Christopher Favazza Junjie Yao Ruimin Chen Qifa Zhou K Kirk Shung Lihong V Wang |
| author_facet | Joon Mo Yang Christopher Favazza Junjie Yao Ruimin Chen Qifa Zhou K Kirk Shung Lihong V Wang |
| author_sort | Joon Mo Yang |
| collection | DOAJ |
| description | We report photoacoustic and ultrasonic endoscopic images of two intact rabbit esophagi. To investigate the esophageal lumen structure and microvasculature, we performed in vivo and ex vivo imaging studies using a 3.8-mm diameter photoacoustic endoscope and correlated the images with histology. Several interesting anatomic structures were newly found in both the in vivo and ex vivo images, which demonstrates the potential clinical utility of this endoscopic imaging modality. In the ex vivo imaging experiment, we acquired high-resolution motion-artifact-free three-dimensional photoacoustic images of the vasculatures distributed in the walls of the esophagi and extending to the neighboring mediastinal regions. Blood vessels with apparent diameters as small as 190 μm were resolved. Moreover, by taking advantage of the dual-mode high-resolution photoacoustic and ultrasound endoscopy, we could better identify and characterize the anatomic structures of the esophageal lumen, such as the mucosal and submucosal layers in the esophageal wall, and an esophageal branch of the thoracic aorta. In this paper, we present the first photoacoustic images showing the vasculature of a vertebrate esophagus and discuss the potential clinical applications and future development of photoacoustic endoscopy. |
| first_indexed | 2024-12-10T05:11:05Z |
| format | Article |
| id | doaj.art-a74e65d11d8c4a2989d2af43839b7fec |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-10T05:11:05Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-a74e65d11d8c4a2989d2af43839b7fec2022-12-22T02:01:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01104e012026910.1371/journal.pone.0120269Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus.Joon Mo YangChristopher FavazzaJunjie YaoRuimin ChenQifa ZhouK Kirk ShungLihong V WangWe report photoacoustic and ultrasonic endoscopic images of two intact rabbit esophagi. To investigate the esophageal lumen structure and microvasculature, we performed in vivo and ex vivo imaging studies using a 3.8-mm diameter photoacoustic endoscope and correlated the images with histology. Several interesting anatomic structures were newly found in both the in vivo and ex vivo images, which demonstrates the potential clinical utility of this endoscopic imaging modality. In the ex vivo imaging experiment, we acquired high-resolution motion-artifact-free three-dimensional photoacoustic images of the vasculatures distributed in the walls of the esophagi and extending to the neighboring mediastinal regions. Blood vessels with apparent diameters as small as 190 μm were resolved. Moreover, by taking advantage of the dual-mode high-resolution photoacoustic and ultrasound endoscopy, we could better identify and characterize the anatomic structures of the esophageal lumen, such as the mucosal and submucosal layers in the esophageal wall, and an esophageal branch of the thoracic aorta. In this paper, we present the first photoacoustic images showing the vasculature of a vertebrate esophagus and discuss the potential clinical applications and future development of photoacoustic endoscopy.http://europepmc.org/articles/PMC4398324?pdf=render |
| spellingShingle | Joon Mo Yang Christopher Favazza Junjie Yao Ruimin Chen Qifa Zhou K Kirk Shung Lihong V Wang Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus. PLoS ONE |
| title | Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus. |
| title_full | Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus. |
| title_fullStr | Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus. |
| title_full_unstemmed | Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus. |
| title_short | Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus. |
| title_sort | three dimensional photoacoustic endoscopic imaging of the rabbit esophagus |
| url | http://europepmc.org/articles/PMC4398324?pdf=render |
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