Prevalence of microbiological markers in bone tissue from live and cadaver donors in the musculoskeletal tissue bank of Passo Fundo

Objective:To conduct an epidemiological analysis on the main microbiological markers in bone tissue that was processed at the musculoskeletal tissue bank of Hospital São Vicente de Paulo, in Passo Fundo, between August 2007 and October 2011.Methods:Between August 2007 and October 2011, 202 musculosk...

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Main Authors: Bruno Dutra Roos, Milton Valdomiro Roos, Antero Camisa Júnior, Ezequiel Moreno Ungaretti Lima, Rafael Noshang Pereira, Maurício Luciano Zangirolami, Gisela Machado de Albuquerque
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2014-08-01
Series:Revista Brasileira de Ortopedia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162014000400386&lng=en&tlng=en
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author Bruno Dutra Roos
Milton Valdomiro Roos
Antero Camisa Júnior
Ezequiel Moreno Ungaretti Lima
Rafael Noshang Pereira
Maurício Luciano Zangirolami
Gisela Machado de Albuquerque
author_facet Bruno Dutra Roos
Milton Valdomiro Roos
Antero Camisa Júnior
Ezequiel Moreno Ungaretti Lima
Rafael Noshang Pereira
Maurício Luciano Zangirolami
Gisela Machado de Albuquerque
author_sort Bruno Dutra Roos
collection DOAJ
description Objective:To conduct an epidemiological analysis on the main microbiological markers in bone tissue that was processed at the musculoskeletal tissue bank of Hospital São Vicente de Paulo, in Passo Fundo, between August 2007 and October 2011.Methods:Between August 2007 and October 2011, 202 musculoskeletal tissue samples were collected for the tissue bank. Among these, 159 samples were from living donor patients and 43 were from cadaver donors. The following serological tests were requested: hepatitis B, hepatitis C, syphilis, cytomegalovirus, Chagas disease, toxoplasmosis, HIV and HTLV.Results:Among the 159 living donors, 103 (64.75%) were men and 56 (35.25%) were women. The patients' mean age was 59.35 ± 8.87 years. Out of this total, 76 tissue samples (47.8%) from donors were rejected. There was no difference in the number of rejections in relation to sex (p = 0.135) or age (p = 0.523). The main cause of rejection was serologically positive findings for the hepatitis B virus, which was responsible for 48 rejections (63.15%). Among the 43 cadaver donors, the mean age was 37.84 ± 10.32 years. Of these, 27 (62.8%) were men and 16 (37.2%) were women. Six of the samples collected from cadaver donors were rejected (13.9%), and the main cause of rejection was serologically positive findings for the hepatitis C virus, which was responsible for three cases (50%). There was no significant difference in the number of rejections in relation to sex (p = 0.21) or age (p = 0.252).Conclusion:There were a greater number of rejections of tissues from living donors (47.8%) than from cadaver donors (13.9%). Among the living donors, the main cause of rejection was the presence of serologically positive findings of the hepatitis B virus, while among the cadaver donors, it was due to the hepatitis C virus.
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spelling doaj.art-a7550bdd1b5c4aeb910a1b5479f1c8dc2024-04-28T09:05:26ZengThieme Revinter Publicações Ltda.Revista Brasileira de Ortopedia1982-43782014-08-0149438639010.1016/j.rboe.2014.03.005S0102-36162014000400386Prevalence of microbiological markers in bone tissue from live and cadaver donors in the musculoskeletal tissue bank of Passo FundoBruno Dutra RoosMilton Valdomiro RoosAntero Camisa JúniorEzequiel Moreno Ungaretti LimaRafael Noshang PereiraMaurício Luciano ZangirolamiGisela Machado de AlbuquerqueObjective:To conduct an epidemiological analysis on the main microbiological markers in bone tissue that was processed at the musculoskeletal tissue bank of Hospital São Vicente de Paulo, in Passo Fundo, between August 2007 and October 2011.Methods:Between August 2007 and October 2011, 202 musculoskeletal tissue samples were collected for the tissue bank. Among these, 159 samples were from living donor patients and 43 were from cadaver donors. The following serological tests were requested: hepatitis B, hepatitis C, syphilis, cytomegalovirus, Chagas disease, toxoplasmosis, HIV and HTLV.Results:Among the 159 living donors, 103 (64.75%) were men and 56 (35.25%) were women. The patients' mean age was 59.35 ± 8.87 years. Out of this total, 76 tissue samples (47.8%) from donors were rejected. There was no difference in the number of rejections in relation to sex (p = 0.135) or age (p = 0.523). The main cause of rejection was serologically positive findings for the hepatitis B virus, which was responsible for 48 rejections (63.15%). Among the 43 cadaver donors, the mean age was 37.84 ± 10.32 years. Of these, 27 (62.8%) were men and 16 (37.2%) were women. Six of the samples collected from cadaver donors were rejected (13.9%), and the main cause of rejection was serologically positive findings for the hepatitis C virus, which was responsible for three cases (50%). There was no significant difference in the number of rejections in relation to sex (p = 0.21) or age (p = 0.252).Conclusion:There were a greater number of rejections of tissues from living donors (47.8%) than from cadaver donors (13.9%). Among the living donors, the main cause of rejection was the presence of serologically positive findings of the hepatitis B virus, while among the cadaver donors, it was due to the hepatitis C virus.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162014000400386&lng=en&tlng=enBancos de ossosTransplante homólogo/efeito adversoDoenças viraisInfecções bacterianas
spellingShingle Bruno Dutra Roos
Milton Valdomiro Roos
Antero Camisa Júnior
Ezequiel Moreno Ungaretti Lima
Rafael Noshang Pereira
Maurício Luciano Zangirolami
Gisela Machado de Albuquerque
Prevalence of microbiological markers in bone tissue from live and cadaver donors in the musculoskeletal tissue bank of Passo Fundo
Revista Brasileira de Ortopedia
Bancos de ossos
Transplante homólogo/efeito adverso
Doenças virais
Infecções bacterianas
title Prevalence of microbiological markers in bone tissue from live and cadaver donors in the musculoskeletal tissue bank of Passo Fundo
title_full Prevalence of microbiological markers in bone tissue from live and cadaver donors in the musculoskeletal tissue bank of Passo Fundo
title_fullStr Prevalence of microbiological markers in bone tissue from live and cadaver donors in the musculoskeletal tissue bank of Passo Fundo
title_full_unstemmed Prevalence of microbiological markers in bone tissue from live and cadaver donors in the musculoskeletal tissue bank of Passo Fundo
title_short Prevalence of microbiological markers in bone tissue from live and cadaver donors in the musculoskeletal tissue bank of Passo Fundo
title_sort prevalence of microbiological markers in bone tissue from live and cadaver donors in the musculoskeletal tissue bank of passo fundo
topic Bancos de ossos
Transplante homólogo/efeito adverso
Doenças virais
Infecções bacterianas
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-36162014000400386&lng=en&tlng=en
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