DLX5 promotes Col10a1 expression and chondrocyte hypertrophy and is involved in osteoarthritis progression

DLX5 promotes Col10a1 expression and chondrocyte hypertrophy and is involved in osteoarthritis progression

Osteoarthritis (OA) has been considered non-reversible as articular cartilage wears down with limited repair capacity. Enhanced chondrocyte hypertrophy and increased type X collagen gene (COL10A1) expression have been associated with OA. Therefore, regulators controlling collagen X expression and ch...

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Bibliographic Details
Main Authors: Jinnan Chen, Fangzhou Chen, Xuan Wu, Huiqin Bian, Chen Chen, Xiaojing Zhang, Ruoxuan Hei, XiaotongYang, Haochun Yuan, Qian Wang, Yaojuan Lu, Longwei Qiao, Qiping Zheng
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Genes and Diseases
Subjects:
Chondrocyte hypertrophy
Col10a1 expression
DLX5
Osteoarthritis
RUNX2
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304223000132

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