Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage
effects of oral misoprostol versus syntometrine for prevention of primary postpartum hemorrhage. Methods: Interventional study; Eighty patients were divided into two equal groups. Misoprostol 600 microgram single dose was given orally immediately after cord clamping to Group A. Syntometrine (consist...
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Format: | Article |
Language: | English |
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Rawalpindi Medical University
2010-06-01
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Series: | Journal of Rawalpindi Medical College |
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Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/716 |
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author | Sehrana Kousar |
author_facet | Sehrana Kousar |
author_sort | Sehrana Kousar |
collection | DOAJ |
description | effects of oral misoprostol versus syntometrine for prevention of primary postpartum hemorrhage. Methods: Interventional study; Eighty patients were divided into two equal groups. Misoprostol 600 microgram single dose was given orally immediately after cord clamping to Group A. Syntometrine (consists of 10 IU oxytocin + 0.5mg ergometrine) was given intravenous to Group B. Patients were kept under observation for 6 hours. Pulse, blood pressure, temperature any need for other uterotonic drugs, estimated blood loss (<500ml or >500ml) haemoglobin percentage 6hours before and after delivery, need for blood transfusion, side effects, time and mode of delivery were noted. Results: Differences in blood pressure and transfusion were statistically insignificant between two groups. Shivering and pyrexia was more common in Group A , and nausea, vomiting and hypertension in Group B Conclusion: Like syntometrine, misoprostol can be used prophylactically orally during third stage of labour to reduce the incidence of Primary postpartum hemorrhage. |
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format | Article |
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institution | Directory Open Access Journal |
issn | 1683-3562 1683-3570 |
language | English |
last_indexed | 2024-12-11T17:51:08Z |
publishDate | 2010-06-01 |
publisher | Rawalpindi Medical University |
record_format | Article |
series | Journal of Rawalpindi Medical College |
spelling | doaj.art-a75f61fd08854cab81eb5c52f40bbc652022-12-22T00:56:12ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702010-06-01141Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum HemorrhageSehrana Kousar0Department of Gynae/Obs, District Head Quarters Teaching Hospital Rawalpindieffects of oral misoprostol versus syntometrine for prevention of primary postpartum hemorrhage. Methods: Interventional study; Eighty patients were divided into two equal groups. Misoprostol 600 microgram single dose was given orally immediately after cord clamping to Group A. Syntometrine (consists of 10 IU oxytocin + 0.5mg ergometrine) was given intravenous to Group B. Patients were kept under observation for 6 hours. Pulse, blood pressure, temperature any need for other uterotonic drugs, estimated blood loss (<500ml or >500ml) haemoglobin percentage 6hours before and after delivery, need for blood transfusion, side effects, time and mode of delivery were noted. Results: Differences in blood pressure and transfusion were statistically insignificant between two groups. Shivering and pyrexia was more common in Group A , and nausea, vomiting and hypertension in Group B Conclusion: Like syntometrine, misoprostol can be used prophylactically orally during third stage of labour to reduce the incidence of Primary postpartum hemorrhage.https://www.journalrmc.com/index.php/JRMC/article/view/716Primary postpartum hemorrhageuterine atonyProstaglandinsoxytocinergot alkal |
spellingShingle | Sehrana Kousar Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage Journal of Rawalpindi Medical College Primary postpartum hemorrhage uterine atony Prostaglandins oxytocin ergot alkal |
title | Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage |
title_full | Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage |
title_fullStr | Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage |
title_full_unstemmed | Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage |
title_short | Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage |
title_sort | efficacy of misoprostol versus syntometrine in the prevention of postpartum hemorrhage |
topic | Primary postpartum hemorrhage uterine atony Prostaglandins oxytocin ergot alkal |
url | https://www.journalrmc.com/index.php/JRMC/article/view/716 |
work_keys_str_mv | AT sehranakousar efficacyofmisoprostolversussyntometrineinthepreventionofpostpartumhemorrhage |