Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage

effects of oral misoprostol versus syntometrine for prevention of primary postpartum hemorrhage. Methods: Interventional study; Eighty patients were divided into two equal groups. Misoprostol 600 microgram single dose was given orally immediately after cord clamping to Group A. Syntometrine (consist...

Full description

Bibliographic Details
Main Author: Sehrana Kousar
Format: Article
Language:English
Published: Rawalpindi Medical University 2010-06-01
Series:Journal of Rawalpindi Medical College
Subjects:
Online Access:https://www.journalrmc.com/index.php/JRMC/article/view/716
_version_ 1818532867391619072
author Sehrana Kousar
author_facet Sehrana Kousar
author_sort Sehrana Kousar
collection DOAJ
description effects of oral misoprostol versus syntometrine for prevention of primary postpartum hemorrhage. Methods: Interventional study; Eighty patients were divided into two equal groups. Misoprostol 600 microgram single dose was given orally immediately after cord clamping to Group A. Syntometrine (consists of 10 IU oxytocin + 0.5mg ergometrine) was given intravenous to Group B. Patients were kept under observation for 6 hours. Pulse, blood pressure, temperature any need for other uterotonic drugs, estimated blood loss (<500ml or >500ml) haemoglobin percentage 6hours before and after delivery, need for blood transfusion, side effects, time and mode of delivery were noted. Results: Differences in blood pressure and transfusion were statistically insignificant between two groups. Shivering and pyrexia was more common in Group A , and nausea, vomiting and hypertension in Group B Conclusion: Like syntometrine, misoprostol can be used prophylactically orally during third stage of labour to reduce the incidence of Primary postpartum hemorrhage.
first_indexed 2024-12-11T17:51:08Z
format Article
id doaj.art-a75f61fd08854cab81eb5c52f40bbc65
institution Directory Open Access Journal
issn 1683-3562
1683-3570
language English
last_indexed 2024-12-11T17:51:08Z
publishDate 2010-06-01
publisher Rawalpindi Medical University
record_format Article
series Journal of Rawalpindi Medical College
spelling doaj.art-a75f61fd08854cab81eb5c52f40bbc652022-12-22T00:56:12ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702010-06-01141Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum HemorrhageSehrana Kousar0Department of Gynae/Obs, District Head Quarters Teaching Hospital Rawalpindieffects of oral misoprostol versus syntometrine for prevention of primary postpartum hemorrhage. Methods: Interventional study; Eighty patients were divided into two equal groups. Misoprostol 600 microgram single dose was given orally immediately after cord clamping to Group A. Syntometrine (consists of 10 IU oxytocin + 0.5mg ergometrine) was given intravenous to Group B. Patients were kept under observation for 6 hours. Pulse, blood pressure, temperature any need for other uterotonic drugs, estimated blood loss (<500ml or >500ml) haemoglobin percentage 6hours before and after delivery, need for blood transfusion, side effects, time and mode of delivery were noted. Results: Differences in blood pressure and transfusion were statistically insignificant between two groups. Shivering and pyrexia was more common in Group A , and nausea, vomiting and hypertension in Group B Conclusion: Like syntometrine, misoprostol can be used prophylactically orally during third stage of labour to reduce the incidence of Primary postpartum hemorrhage.https://www.journalrmc.com/index.php/JRMC/article/view/716Primary postpartum hemorrhageuterine atonyProstaglandinsoxytocinergot alkal
spellingShingle Sehrana Kousar
Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage
Journal of Rawalpindi Medical College
Primary postpartum hemorrhage
uterine atony
Prostaglandins
oxytocin
ergot alkal
title Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage
title_full Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage
title_fullStr Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage
title_full_unstemmed Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage
title_short Efficacy of Misoprostol versus Syntometrine in the Prevention of Postpartum Hemorrhage
title_sort efficacy of misoprostol versus syntometrine in the prevention of postpartum hemorrhage
topic Primary postpartum hemorrhage
uterine atony
Prostaglandins
oxytocin
ergot alkal
url https://www.journalrmc.com/index.php/JRMC/article/view/716
work_keys_str_mv AT sehranakousar efficacyofmisoprostolversussyntometrineinthepreventionofpostpartumhemorrhage