Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity
Opioids are highly effective analgesics that have a serious potential for adverse drug reactions and for development of addiction and tolerance. Since the use of opioids has escalated in recent years, it is increasingly important to understand biological mechanisms that can increase the probability...
Main Authors: | Junzhi Yang, Bianca G. Reilly, Thomas P. Davis, Patrick T. Ronaldson |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-10-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4923/10/4/192 |
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