Screening of prototype antiseizure and anti‐inflammatory compounds in the Theiler's murine encephalomyelitis virus model of epilepsy

Screening of prototype antiseizure and anti‐inflammatory compounds in the Theiler's murine encephalomyelitis virus model of epilepsy

Abstract Objective Infection with Theiler's murine encephalomyelitis virus (TMEV) in C57Bl/6J mice results in handling‐induced seizures and is useful for evaluating compounds effective against infection‐induced seizures. However, to date only a few compounds have been evaluated in this model, a...

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Bibliographic Details
Main Authors: Cameron S. Metcalf, Fabiola Vanegas, Tristan Underwood, Kristina Johnson, Peter J. West, Misty D. Smith, Karen S. Wilcox
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:Epilepsia Open
Subjects:
animal models
antiseizure medications
infection‐induced seizures
inflammation
pharmacoresistant epilepsy
Online Access:https://doi.org/10.1002/epi4.12550

Internet

https://doi.org/10.1002/epi4.12550

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