Computer Simulation of a Surface Charge Nanobiosensor with Internal Signal Integration

The ionized states of molecular analytes located on solid surfaces require profound investigation and better understanding for applications in the basic sciences in general, and in the design of nanobiosensors, in particular. Such ionized states are induced by the interactions of molecules between t...

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Main Authors: Dmitry Dyubo, Oleg Yu. Tsybin
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/11/10/397
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author Dmitry Dyubo
Oleg Yu. Tsybin
author_facet Dmitry Dyubo
Oleg Yu. Tsybin
author_sort Dmitry Dyubo
collection DOAJ
description The ionized states of molecular analytes located on solid surfaces require profound investigation and better understanding for applications in the basic sciences in general, and in the design of nanobiosensors, in particular. Such ionized states are induced by the interactions of molecules between them in the analyzed substance and with the target surface. Here, computer simulations using COMSOL Multiphysics software show the effect of surface charge density and distribution on the output generation in a dynamic PIN diode with gate control. This device, having built-in potential barriers, has a unique internal integration of output signal generation. The identified interactions showed the possibility of a new design for implementing a nanobiosensor based on a dynamic PIN diode in a mode with surface charge control.
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spelling doaj.art-a77152f6c7c640c2831f098adab49b912023-11-22T17:36:07ZengMDPI AGBiosensors2079-63742021-10-01111039710.3390/bios11100397Computer Simulation of a Surface Charge Nanobiosensor with Internal Signal IntegrationDmitry Dyubo0Oleg Yu. Tsybin1Institute of Electronics and Telecommunications, Peter the Great St. Petersburg Polytechnical University, Polytechnicheskaya, 29, 195251 St. Petersburg, RussiaInstitute of Electronics and Telecommunications, Peter the Great St. Petersburg Polytechnical University, Polytechnicheskaya, 29, 195251 St. Petersburg, RussiaThe ionized states of molecular analytes located on solid surfaces require profound investigation and better understanding for applications in the basic sciences in general, and in the design of nanobiosensors, in particular. Such ionized states are induced by the interactions of molecules between them in the analyzed substance and with the target surface. Here, computer simulations using COMSOL Multiphysics software show the effect of surface charge density and distribution on the output generation in a dynamic PIN diode with gate control. This device, having built-in potential barriers, has a unique internal integration of output signal generation. The identified interactions showed the possibility of a new design for implementing a nanobiosensor based on a dynamic PIN diode in a mode with surface charge control.https://www.mdpi.com/2079-6374/11/10/397surface chargenanobiosensorcomputer simulationCOMSOL Multiphysics
spellingShingle Dmitry Dyubo
Oleg Yu. Tsybin
Computer Simulation of a Surface Charge Nanobiosensor with Internal Signal Integration
Biosensors
surface charge
nano
biosensor
computer simulation
COMSOL Multiphysics
title Computer Simulation of a Surface Charge Nanobiosensor with Internal Signal Integration
title_full Computer Simulation of a Surface Charge Nanobiosensor with Internal Signal Integration
title_fullStr Computer Simulation of a Surface Charge Nanobiosensor with Internal Signal Integration
title_full_unstemmed Computer Simulation of a Surface Charge Nanobiosensor with Internal Signal Integration
title_short Computer Simulation of a Surface Charge Nanobiosensor with Internal Signal Integration
title_sort computer simulation of a surface charge nanobiosensor with internal signal integration
topic surface charge
nano
biosensor
computer simulation
COMSOL Multiphysics
url https://www.mdpi.com/2079-6374/11/10/397
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