Three-dimensional electron crystallography of protein microcrystals
We demonstrate that it is feasible to determine high-resolution protein structures by electron crystallography of three-dimensional crystals in an electron cryo-microscope (CryoEM). Lysozyme microcrystals were frozen on an electron microscopy grid, and electron diffraction data collected to 1.7 Å re...
Main Authors: | Dan Shi, Brent L Nannenga, Matthew G Iadanza, Tamir Gonen |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2013-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/01345 |
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