Neurons are the Primary Target Cell for the Brain-Tropic Intracellular Parasite Toxoplasma gondii.
Toxoplasma gondii, a common brain-tropic parasite, is capable of infecting most nucleated cells, including astrocytes and neurons, in vitro. Yet, in vivo, Toxoplasma is primarily found in neurons. In vitro data showing that interferon-γ-stimulated astrocytes, but not neurons, clear intracellular par...
Main Authors: | Carla M Cabral, Shraddha Tuladhar, Hans K Dietrich, Elizabeth Nguyen, Wes R MacDonald, Tapasya Trivedi, Asha Devineni, Anita A Koshy |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-02-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4760770?pdf=render |
Similar Items
-
IFN-γ stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii
by: Sambamurthy Chandrasekaran, et al.
Published: (2022-08-01) -
Cathepsin Cs are key for the intracellular survival of the protozoan parasite, Toxoplasma gondii.
by: Que, X, et al.
Published: (2007) -
Genomic insights into host and parasite interactions during intracellular infection by Toxoplasma gondii.
by: Netha Ulahannan, et al.
Published: (2022-01-01) -
Toxoplasma gondii: the kitty litter parasite
by: Aisha Al-Janabi, et al.
Published: (2022-12-01) -
The Apicomplexan Parasite <i>Toxoplasma gondii</i>
by: Inês L. S. Delgado, et al.
Published: (2022-01-01)