Experimental validation of proton boron capture therapy for glioma cells

Abstract Proton boron capture therapy (PBCT) has emerged from particle acceleration research for enhancing the biological effectiveness of proton therapy. The mechanism responsible for the dose increase was supposed to be related to proton-boron fusion reactions (11B + p → 3α + 8.7 MeV). There has b...

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Bibliographic Details
Main Authors: Tatiana Shtam, Vladimir Burdakov, Alina Garina, Luiza Garaeva, Nhan Hau Tran, Andrey Volnitskiy, Eva Kuus, Dmitry Amerkanov, Fedor Pack, Georgy Andreev, Andrey Lubinskiy, Konstantin Shabalin, Nicolay Verlov, Evgeniy Ivanov, Victor Ezhov, Dmitry Lebedev, Andrey L. Konevega
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28428-z