Contribution of H3K4 demethylase KDM5B to nucleosome organization in embryonic stem cells revealed by micrococcal nuclease sequencing

Contribution of H3K4 demethylase KDM5B to nucleosome organization in embryonic stem cells revealed by micrococcal nuclease sequencing

Abstract Background Positioning of nucleosomes along DNA is an integral regulator of chromatin accessibility and gene expression in diverse cell types. However, the precise nature of how histone demethylases including the histone 3 lysine 4 (H3K4) demethylase, KDM5B, impacts nucleosome positioning a...

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Bibliographic Details
Main Authors: Jiji T. Kurup, Ion J. Campeanu, Benjamin L. Kidder
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Epigenetics & Chromatin
Subjects:
Embryonic stem cells
Pluripotent
Epigenetics
Micrococcal nuclease
MNase
Nucleosome positioning
Online Access:http://link.springer.com/article/10.1186/s13072-019-0266-9

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