The salivary gland salivation stimulating peptide from Locusta migratoria (Lom-SG-SASP) is not a typical neuropeptide
The salivary gland salivation stimulating peptide was identified from the salivary glands of the migratory locust by its ability to stimulate cAMP production in the same tissue. The gene coding for this peptide has recently been identified and been shown to code for a precursor consisting of a signa...
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| Format: | Article |
| Language: | English |
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PeerJ Inc.
2017-07-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/3619.pdf |
| _version_ | 1797422181165039616 |
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| author | Jan A. Veenstra |
| author_facet | Jan A. Veenstra |
| author_sort | Jan A. Veenstra |
| collection | DOAJ |
| description | The salivary gland salivation stimulating peptide was identified from the salivary glands of the migratory locust by its ability to stimulate cAMP production in the same tissue. The gene coding for this peptide has recently been identified and been shown to code for a precursor consisting of a signal peptide, several copies of the peptide separated by Lys–Arg doublets and a few other peptides. These data are consistent with it being a neuropeptide. However, antiserum raised to this peptide labels the acini of the salivary glands while RT-PCR only gives positive results in the salivary gland, but not in any ganglion of the central nervous system. Thus, this peptide is not a typical neuropeptide as previously assumed. |
| first_indexed | 2024-03-09T07:28:28Z |
| format | Article |
| id | doaj.art-a77fa259d54244f58620677d1e7e3297 |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T07:28:28Z |
| publishDate | 2017-07-01 |
| publisher | PeerJ Inc. |
| record_format | Article |
| series | PeerJ |
| spelling | doaj.art-a77fa259d54244f58620677d1e7e32972023-12-03T06:48:28ZengPeerJ Inc.PeerJ2167-83592017-07-015e361910.7717/peerj.3619The salivary gland salivation stimulating peptide from Locusta migratoria (Lom-SG-SASP) is not a typical neuropeptideJan A. VeenstraThe salivary gland salivation stimulating peptide was identified from the salivary glands of the migratory locust by its ability to stimulate cAMP production in the same tissue. The gene coding for this peptide has recently been identified and been shown to code for a precursor consisting of a signal peptide, several copies of the peptide separated by Lys–Arg doublets and a few other peptides. These data are consistent with it being a neuropeptide. However, antiserum raised to this peptide labels the acini of the salivary glands while RT-PCR only gives positive results in the salivary gland, but not in any ganglion of the central nervous system. Thus, this peptide is not a typical neuropeptide as previously assumed.https://peerj.com/articles/3619.pdfRT-PCRPC1ImmunohistologySG-SASPPC2Antiserum |
| spellingShingle | Jan A. Veenstra The salivary gland salivation stimulating peptide from Locusta migratoria (Lom-SG-SASP) is not a typical neuropeptide PeerJ RT-PCR PC1 Immunohistology SG-SASP PC2 Antiserum |
| title | The salivary gland salivation stimulating peptide from Locusta migratoria (Lom-SG-SASP) is not a typical neuropeptide |
| title_full | The salivary gland salivation stimulating peptide from Locusta migratoria (Lom-SG-SASP) is not a typical neuropeptide |
| title_fullStr | The salivary gland salivation stimulating peptide from Locusta migratoria (Lom-SG-SASP) is not a typical neuropeptide |
| title_full_unstemmed | The salivary gland salivation stimulating peptide from Locusta migratoria (Lom-SG-SASP) is not a typical neuropeptide |
| title_short | The salivary gland salivation stimulating peptide from Locusta migratoria (Lom-SG-SASP) is not a typical neuropeptide |
| title_sort | salivary gland salivation stimulating peptide from locusta migratoria lom sg sasp is not a typical neuropeptide |
| topic | RT-PCR PC1 Immunohistology SG-SASP PC2 Antiserum |
| url | https://peerj.com/articles/3619.pdf |
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