Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance during General Anesthesia—A New Era in Patient Safety Standards and Healthcare Management

The development of general anesthesia techniques and anesthetic substances has opened new horizons for the expansion and improvement of surgical techniques. Nevertheless, more complex surgical procedures have brought a higher complexity and longer duration for general anesthesia, which has led to a...

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Main Authors: Alexandru Florin Rogobete, Ovidiu Horea Bedreag, Marius Papurica, Sonia Elena Popovici, Lavinia Melania Bratu, Andreea Rata, Claudiu Rafael Barsac, Andra Maghiar, Dragos Nicolae Garofil, Mihai Negrea, Laura Bostangiu Petcu, Daiana Toma, Corina Maria Dumbuleu, Samir Rimawi, Dorel Sandesc
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1010-660X/57/2/132
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author Alexandru Florin Rogobete
Ovidiu Horea Bedreag
Marius Papurica
Sonia Elena Popovici
Lavinia Melania Bratu
Andreea Rata
Claudiu Rafael Barsac
Andra Maghiar
Dragos Nicolae Garofil
Mihai Negrea
Laura Bostangiu Petcu
Daiana Toma
Corina Maria Dumbuleu
Samir Rimawi
Dorel Sandesc
author_facet Alexandru Florin Rogobete
Ovidiu Horea Bedreag
Marius Papurica
Sonia Elena Popovici
Lavinia Melania Bratu
Andreea Rata
Claudiu Rafael Barsac
Andra Maghiar
Dragos Nicolae Garofil
Mihai Negrea
Laura Bostangiu Petcu
Daiana Toma
Corina Maria Dumbuleu
Samir Rimawi
Dorel Sandesc
author_sort Alexandru Florin Rogobete
collection DOAJ
description The development of general anesthesia techniques and anesthetic substances has opened new horizons for the expansion and improvement of surgical techniques. Nevertheless, more complex surgical procedures have brought a higher complexity and longer duration for general anesthesia, which has led to a series of adverse events such as hemodynamic instability, under- or overdosage of anesthetic drugs, and an increased number of post-anesthetic events. In order to adapt the anesthesia according to the particularities of each patient, the multimodal monitoring of these patients is highly recommended. Classically, general anesthesia monitoring consists of the analysis of vital functions and gas exchange. Multimodal monitoring refers to the concomitant monitoring of the degree of hypnosis and the nociceptive-antinociceptive balance. By titrating anesthetic drugs according to these parameters, clinical benefits can be obtained, such as hemodynamic stabilization, the reduction of awakening times, and the reduction of postoperative complications. Another important aspect is the impact on the status of inflammation and the redox balance. By minimizing inflammatory and oxidative impact, a faster recovery can be achieved that increases patient safety. The purpose of this literature review is to present the most modern multimodal monitoring techniques to discuss the particularities of each technique.
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spelling doaj.art-a782cab879364b32ad126363d82c33602023-09-02T18:01:50ZengMDPI AGMedicina1010-660X2021-02-015713213210.3390/medicina57020132Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance during General Anesthesia—A New Era in Patient Safety Standards and Healthcare ManagementAlexandru Florin Rogobete0Ovidiu Horea Bedreag1Marius Papurica2Sonia Elena Popovici3Lavinia Melania Bratu4Andreea Rata5Claudiu Rafael Barsac6Andra Maghiar7Dragos Nicolae Garofil8Mihai Negrea9Laura Bostangiu Petcu10Daiana Toma11Corina Maria Dumbuleu12Samir Rimawi13Dorel Sandesc14Faculty of Medicine, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaFaculty of Medicine, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaFaculty of Medicine, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaFaculty of Medicine, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaFaculty of Medicine, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaDepartment of Vascular Surgery, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaFaculty of Medicine, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaFaculty of Medicine, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, RomaniaFaculty of Political, Administrative and Communication Sciences, Babes-Bolyai University, 400376 Cluj Napoca, RomaniaFaculty of Management, The Bucharest University of Economic Studies, 020021 Bucharest, RomaniaAnaesthesia and Intensive Care Research Center, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaAnaesthesia and Intensive Care Research Center, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaClinic of Anaesthesia and Intensive Care, Emergency County Hospital “Pius Brinzeu”, 300723 Timisoara, RomaniaFaculty of Medicine, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaThe development of general anesthesia techniques and anesthetic substances has opened new horizons for the expansion and improvement of surgical techniques. Nevertheless, more complex surgical procedures have brought a higher complexity and longer duration for general anesthesia, which has led to a series of adverse events such as hemodynamic instability, under- or overdosage of anesthetic drugs, and an increased number of post-anesthetic events. In order to adapt the anesthesia according to the particularities of each patient, the multimodal monitoring of these patients is highly recommended. Classically, general anesthesia monitoring consists of the analysis of vital functions and gas exchange. Multimodal monitoring refers to the concomitant monitoring of the degree of hypnosis and the nociceptive-antinociceptive balance. By titrating anesthetic drugs according to these parameters, clinical benefits can be obtained, such as hemodynamic stabilization, the reduction of awakening times, and the reduction of postoperative complications. Another important aspect is the impact on the status of inflammation and the redox balance. By minimizing inflammatory and oxidative impact, a faster recovery can be achieved that increases patient safety. The purpose of this literature review is to present the most modern multimodal monitoring techniques to discuss the particularities of each technique.https://www.mdpi.com/1010-660X/57/2/132hypnosismultimodal monitoringentropyqNOXqCONbispectral index
spellingShingle Alexandru Florin Rogobete
Ovidiu Horea Bedreag
Marius Papurica
Sonia Elena Popovici
Lavinia Melania Bratu
Andreea Rata
Claudiu Rafael Barsac
Andra Maghiar
Dragos Nicolae Garofil
Mihai Negrea
Laura Bostangiu Petcu
Daiana Toma
Corina Maria Dumbuleu
Samir Rimawi
Dorel Sandesc
Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance during General Anesthesia—A New Era in Patient Safety Standards and Healthcare Management
Medicina
hypnosis
multimodal monitoring
entropy
qNOX
qCON
bispectral index
title Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance during General Anesthesia—A New Era in Patient Safety Standards and Healthcare Management
title_full Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance during General Anesthesia—A New Era in Patient Safety Standards and Healthcare Management
title_fullStr Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance during General Anesthesia—A New Era in Patient Safety Standards and Healthcare Management
title_full_unstemmed Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance during General Anesthesia—A New Era in Patient Safety Standards and Healthcare Management
title_short Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance during General Anesthesia—A New Era in Patient Safety Standards and Healthcare Management
title_sort multiparametric monitoring of hypnosis and nociception antinociception balance during general anesthesia a new era in patient safety standards and healthcare management
topic hypnosis
multimodal monitoring
entropy
qNOX
qCON
bispectral index
url https://www.mdpi.com/1010-660X/57/2/132
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