Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition.
Despite the increasingly recognized importance of the tumor microenvironment (TME) as a regulator of tumor progression, only few in vitro models have been developed to systematically study the effects of TME on tumor behavior in a controlled manner. Here we developed a three-dimensional (3D) in vitr...
Hlavní autoři: | , , , , , |
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Médium: | Článek |
Jazyk: | English |
Vydáno: |
Public Library of Science (PLoS)
2018-01-01
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Edice: | PLoS ONE |
On-line přístup: | http://europepmc.org/articles/PMC5863989?pdf=render |